Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HRH3 | Q9Y5N1 | 2/20 | 0.36 |
| ▸ | PTGS1 | P23219 | 2/20 | 0.36 |
| ▸ | PTGS2 | P35354 | 2/20 | 0.36 |
| ▸ | DRD3 | P35462 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | ULK1 | O75385 | 1/20 | 0.34 |
| ▸ | PRMT1 | Q99873 | 1/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | SLC29A1 | Q99808 | 1/20 | 0.33 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.33 |
| ▸ | HTR6 | P50406 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | PKM | P14618 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11188751 | 0.93 | HRH3 (0.37) | HRH3PTGS1PTGS2MEN1KMT2A | |
| SCHEMBL11171930 | 0.91 | L3MBTL1 (0.39) | PTGS1PTGS2MAPTMEN1KMT2A | |
| SCHEMBL11274096 | 0.90 | PTGS2 (0.47) | HRH3PTGS1PTGS2DRD3MAPT | |
| SCHEMBL11258108 | 0.87 | PTGS2 (0.44) | HRH3PTGS1PTGS2DRD3MAPT | |
| Benzophenone SCHEMBL11274102 | 0.84 | HRH3 (0.41) | HRH3DRD3MAPTPOLBPRMT1 | |
| SCHEMBL11271305 | 0.84 | PTGS2 (0.48) | HRH3PTGS1PTGS2MAPTKDM4E | |
| SCHEMBL11171928 | 0.83 | PTGS1 (0.39) | PTGS1PTGS2MAPTTDP1KDM4E | |
| SCHEMBL11256561 | 0.83 | PTGS2 (0.48) | HRH3PTGS1PTGS2MAPTKDM4E | |
| SCHEMBL11261401 | 0.83 | PTGS2 (0.48) | HRH3PTGS1PTGS2MAPTKDM4E | |
| SCHEMBL11180351 | 0.82 | KDM4E (0.38) | PTGS1PTGS2MAPTTDP1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0024282-B1 | BENZOYL DERIVATIVES, THEIR PREPARATION AND THEIR USE AS MEDICINES | Dr. Karl Thomae GmbH (DE) | 1983-05-18 | — | — | EP | disclosed |