Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 11/20 | 0.55 |
| ▸ | TSHR | P16473 | 4/20 | 0.55 |
| ▸ | MAPT | P10636 | 3/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.46 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.43 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.43 |
| ▸ | TP53 | P04637 | 1/20 | 0.42 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | GAA | P10253 | 1/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 2/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | RECQL | P46063 | 1/20 | 0.41 |
| ▸ | NPC1 | O15118 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7164182 | 0.85 | ALDH1A1 (0.52) | ALDH1A1TSHRMAPTKMT2AMEN1 | |
| SCHEMBL11182363 | 0.81 | ALDH1A1 (0.51) | ALDH1A1TSHRMAPTKMT2ASMN1; SMN2 | |
| SCHEMBL9246952 | 0.80 | ALDH1A1 (0.68) | ALDH1A1TSHRMAPTKMT2ASMN1; SMN2 | |
| SCHEMBL7335509 | 0.77 | ALDH1A1 (0.72) | ALDH1A1TSHRMAPTKMT2ASMN1; SMN2 | |
| SCHEMBL11172356 | 0.77 | ALDH1A1 (0.52) | ALDH1A1TSHRMAPTKMT2ASMN1; SMN2 | |
| SCHEMBL8540234 | 0.75 | ALDH1A1 (0.61) | ALDH1A1TSHRMAPTKMT2AMEN1 | |
| SCHEMBL11179462 | 0.74 | MEN1 (0.44) | ALDH1A1TSHRKMT2AMEN1TP53 | |
| SCHEMBL11170076 | 0.74 | CNR1 (0.48) | ALDH1A1TSHRKMT2ASMN1; SMN2NPSR1 | |
| SCHEMBL11650278 | 0.73 | ALDH1A1 (0.58) | ALDH1A1TSHRMAPTKMT2ASMN1; SMN2 | |
| SCHEMBL11177331 | 0.72 | TSHR (0.61) | ALDH1A1TSHRMAPTKMT2AMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4377521-A | ANTILIPEMIC | PFIZER INC. (US) | 1983-03-22 | — | — | US | disclosed |
| US-4138399-A | Sulfamylbenzoic acid | PFIZER INC. (US) | 1979-02-06 | — | — | US | disclosed |
| US-4124590-A | CARDIOVASCULAR DISORDERS, ANTILIPEMIC AGENTS | PFIZER INC. (US) | 1978-11-07 | — | — | US | disclosed |
| US-3992441-A | ANTILIPEMIC | PFIZER INC. (US) | 1976-11-16 | — | — | US | disclosed |