Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.53 |
| ▸ | HPGD | P15428 | 3/20 | 0.53 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.53 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.51 |
| ▸ | TP53 | P04637 | 1/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.47 |
| ▸ | LMNA | P02545 | 1/20 | 0.45 |
| ▸ | PTGS1 | P23219 | 3/20 | 0.44 |
| ▸ | PTGS2 | P35354 | 3/20 | 0.44 |
| ▸ | TGFBR1 | P36897 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.42 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | MAPK13 | O15264 | 1/20 | 0.41 |
| ▸ | RAF1 | P04049 | 1/20 | 0.41 |
| ▸ | MAPK9 | P45984 | 1/20 | 0.41 |
| ▸ | MAPK12 | P53778 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5378775 | 0.89 | KDM4E (0.59) | KDM4EHPGDSMN1; SMN2L3MBTL1TP53 | |
| SCHEMBL1696508 | 0.82 | TP53 (0.53) | KDM4EHPGDSMN1; SMN2L3MBTL1TP53 | |
| SCHEMBL19116734 | 0.82 | L3MBTL1 (0.61) | KDM4EHPGDSMN1; SMN2L3MBTL1TP53 | |
| SCHEMBL9518314 | 0.76 | ADORA3 (0.56) | KDM4EHPGDSMN1; SMN2L3MBTL1ALDH1A1 | |
| Ammonia Solution, Strong SCHEMBL27564581 | 0.75 | ADORA3 (0.55) | KDM4EHPGDSMN1; SMN2L3MBTL1ALDH1A1 | |
| SCHEMBL2020536 | 0.75 | — | — | |
| SCHEMBL3278317 | 0.74 | KDM4E (0.58) | KDM4EHPGDSMN1; SMN2L3MBTL1ALDH1A1 | |
| SCHEMBL9515033 | 0.74 | KDM4E (0.53) | KDM4EHPGDSMN1; SMN2L3MBTL1ALDH1A1 | |
| SCHEMBL29668081 | 0.73 | KDM4E (0.51) | KDM4EHPGDSMN1; SMN2L3MBTL1TP53 | |
| SCHEMBL2050519 | 0.73 | KDM4E (0.51) | KDM4EHPGDSMN1; SMN2L3MBTL1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4410706-A | Preparation of 2-vinylimidazoles by dehydrogenation of 2-ethylimidazoles and 2-ethylimidazolines | AMERICAN CYANAMID COMPANY (US) | 1983-10-18 | — | — | US | claimed |