Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FFAR2 | O15552 | 2/20 | 0.51 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.47 |
| ▸ | POLB | P06746 | 2/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | RECQL | P46063 | 1/20 | 0.41 |
| ▸ | BLM | P54132 | 1/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
| ▸ | ACE | P12821 | 5/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11184479 | 0.89 | FFAR2 (0.52) | FFAR2HSD17B10POLBKMT2AKDM4E | |
| SCHEMBL11180379 | 0.88 | FFAR2 (0.52) | FFAR2HSD17B10POLBKMT2AKDM4E | |
| SCHEMBL11194036 | 0.79 | ACE (0.59) | FFAR2POLBALDH1A1ACE | |
| SCHEMBL11194530 | 0.79 | FFAR2 (0.41) | FFAR2HSD17B10POLBALDH1A1RECQL | |
| SCHEMBL11262988 | 0.79 | POLB (0.48) | FFAR2HSD17B10POLBKMT2AKDM4E | |
| SCHEMBL11184570 | 0.78 | POLB (0.47) | FFAR2HSD17B10POLBKMT2AMEN1 | |
| SCHEMBL11184480 | 0.77 | FFAR2 (0.52) | FFAR2HSD17B10POLBKMT2AKDM4E | |
| SCHEMBL11186430 | 0.77 | ALDH1A1 (0.44) | FFAR2HSD17B10POLBKDM4EALDH1A1 | |
| SCHEMBL11190617 | 0.76 | FFAR2 (0.44) | FFAR2HSD17B10POLBKMT2AKDM4E | |
| SCHEMBL11185141 | 0.76 | GAA (0.66) | FFAR2HSD17B10POLBKMT2AMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4410542-A | HYPOTENSIVE AGENTS, PYRROLINE-1,2-DICARBOXYLIC ACID DERIVATIVES | SANTEN PHARMACEUTICAL CO., LTD. (JP) | 1983-10-18 | — | — | US | disclosed |
| US-4347371-A | HYPERTENSIVE AGENTS; ANTIDIABETIC AGENTS; VISION DEFECTS | SANTEN PHARMACEUTICAL CO., LTD. (JP) | 1982-08-31 | — | — | US | disclosed |