Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FFAR2 | O15552 | 1/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.41 |
| ▸ | POLB | P06746 | 5/20 | 0.41 |
| ▸ | RECQL | P46063 | 2/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | BLM | P54132 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 2/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.34 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | ADORA2B | P29275 | 2/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | ACE | P12821 | 2/20 | 0.32 |
| ▸ | GAA | P10253 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11194045 | 0.79 | ACE (0.51) | FFAR2ALDH1A1POLBKMT2AHPGD | |
| SCHEMBL11263001 | 0.79 | POLB (0.40) | FFAR2HSD17B10ALDH1A1POLBKDM4E | |
| SCHEMBL11189268 | 0.77 | ALDH1A1 (0.44) | ALDH1A1POLBKDM4EMAPTBLM | |
| SCHEMBL11202283 | 0.76 | POLB (0.38) | FFAR2HSD17B10ALDH1A1POLBKDM4E | |
| SCHEMBL11183987 | 0.76 | GAA (0.57) | FFAR2ALDH1A1POLBMEN1KMT2A | |
| SCHEMBL11190606 | 0.76 | FFAR2 (0.51) | FFAR2HSD17B10ALDH1A1POLBRECQL | |
| SCHEMBL11180379 | 0.75 | FFAR2 (0.52) | FFAR2HSD17B10ALDH1A1POLBRECQL | |
| SCHEMBL11192054 | 0.74 | ACE (0.36) | HSD17B10ALDH1A1KDM4EACE | |
| SCHEMBL11219804 | 0.74 | ACE (0.36) | FFAR2ALDH1A1POLBMEN1KMT2A | |
| SCHEMBL11199916 | 0.74 | SMN1; SMN2 (0.44) | ALDH1A1POLBKDM4EMAPTKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4410542-A | HYPOTENSIVE AGENTS, PYRROLINE-1,2-DICARBOXYLIC ACID DERIVATIVES | SANTEN PHARMACEUTICAL CO., LTD. (JP) | 1983-10-18 | — | — | US | disclosed |
| US-4347371-A | HYPERTENSIVE AGENTS; ANTIDIABETIC AGENTS; VISION DEFECTS | SANTEN PHARMACEUTICAL CO., LTD. (JP) | 1982-08-31 | — | — | US | disclosed |