Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FFAR1 | O14842 | 1/20 | 0.34 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.30 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7988273 | 0.81 | BUB1 (0.35) | — | |
| SCHEMBL11965050 | 0.80 | FFAR1 (0.37) | FFAR1RXFP1ALDH1A1 | |
| SCHEMBL17871076 | 0.78 | — | — | |
| SCHEMBL6179345 | 0.76 | KMT2A (0.38) | FFAR1RXFP1ALDH1A1 | |
| SCHEMBL30949899 | 0.75 | LOXL2 (0.42) | FFAR1 | |
| SCHEMBL30032050 | 0.75 | RECQL (0.39) | FFAR1ALDH1A1 | |
| SCHEMBL5742153 | 0.75 | RECQL (0.39) | FFAR1ALDH1A1 | |
| SCHEMBL7488587 | 0.74 | MEN1 (0.40) | ALDH1A1 | |
| SCHEMBL996549 | 0.73 | SMN1; SMN2 (0.41) | ALDH1A1 | |
| SCHEMBL737167 | 0.72 | CCR1 (0.47) | FFAR1RXFP1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2280945-A1 | TRISUBSTITUTED PYRAZOLES AS ACETYLCHOLINE RECEPTOR MODULATORS | Janssen Pharmaceutica, N.V. (BE) | 2011-02-09 | — | — | EP | disclosed |
| WO-2009135944-A1 | TRISUBSTITUTED PYRAZOLES AS ACETYLCHOLINE RECEPTOR MODULATORS | JANSSEN PHARMACEUTICA NV (BE) | 2009-11-12 | — | — | WO | disclosed |
| EP-2094682-A2 | HETEROARYL-HETEROARYL COMPOUNDS AS CDK INHIBITORS FOR THE TREATMENT OF CANCER, INFLAMMATION AND VIRAL INFECTIONS | Novartis AG (CH) | 2009-09-02 | — | — | EP | disclosed |
| WO-2008079933-A2 | HETEROARYL-HETEROARYL COMPOUNDS AS CDK INHIBITORS FOR THE TREATMENT OF CANCER, INFLAMMATION AND VIRAL INFECTIONS | NOVARTIS AG (CH) | 2008-07-03 | — | — | WO | disclosed |