Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 3/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.40 |
| ▸ | KDR | P35968 | 1/20 | 0.38 |
| ▸ | DRD2 | P14416 | 2/20 | 0.37 |
| ▸ | DRD4 | P21917 | 2/20 | 0.37 |
| ▸ | DRD3 | P35462 | 2/20 | 0.37 |
| ▸ | METAP2 | P50579 | 1/20 | 0.35 |
| ▸ | BCL2L1 | Q07817 | 1/20 | 0.35 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.35 |
| ▸ | NPC1 | O15118 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | MPI | P34949 | 1/20 | 0.35 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
| ▸ | RAB9A | P51151 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7495227 | 0.83 | KMT2A (0.40) | MEN1KMT2AKDRBCL2L1NPSR1 | |
| SCHEMBL27565020 | 0.82 | MEN1 (0.34) | MEN1KMT2AKDRDRD2DRD4 | |
| SCHEMBL6180952 | 0.80 | KMT2A (0.53) | MEN1KMT2AKDRNPSR1NPC1 | |
| SCHEMBL27565019 | 0.76 | MEN1 (0.41) | MEN1KMT2AKDRDRD2DRD4 | |
| SCHEMBL1119082 | 0.74 | FFAR1 (0.34) | ALDH1A1 | |
| SCHEMBL28868529 | 0.73 | PDCD1 (0.52) | MEN1KMT2ANPSR1MAPTALDH1A1 | |
| SCHEMBL11965050 | 0.69 | FFAR1 (0.37) | MAPTALDH1A1KDM4ELMNASMN1; SMN2 | |
| SCHEMBL27565013 | 0.68 | DRD2 (0.34) | MEN1KMT2ADRD2DRD4DRD3 | |
| SCHEMBL2367290 | 0.67 | DRD2 (0.32) | DRD2DRD4DRD3ALDH1A1 | |
| SCHEMBL27318730 | 0.66 | ALDH1A1 (0.49) | MEN1KMT2AMETAP2NPSR1NPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1218376-A4 | TYROSINE KINASE INHIBITORS | MERCK & CO INC (US) | 2002-11-20 | — | — | EP | disclosed |
| EP-1218376-A1 | TYROSINE KINASE INHIBITORS | Merck & Co., Inc. (US) | 2002-07-03 | — | — | EP | disclosed |
| WO-2001017995-A1 | TYROSINE KINASE INHIBITORS | MERCK & CO., INC. (US) | 2001-03-15 | — | — | WO | disclosed |