Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 2/20 | 0.38 |
| ▸ | GAA | P10253 | 2/20 | 0.38 |
| ▸ | MAPT | P10636 | 2/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.38 |
| ▸ | BCHE | P06276 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.38 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.38 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.38 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.38 |
| ▸ | MAOA | P21397 | 1/20 | 0.38 |
| ▸ | CNR1 | P21554 | 1/20 | 0.38 |
| ▸ | ACHE | P22303 | 1/20 | 0.38 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.38 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.38 |
| ▸ | HTR2C | P28335 | 1/20 | 0.38 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.38 |
| ▸ | SNCA | P37840 | 1/20 | 0.38 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11199300 | 0.86 | GAA (0.46) | MEN1GAAMAPTKMT2ACYP1A2 | |
| SCHEMBL10989509 | 0.84 | GGT1 (0.47) | MEN1GAAMAPTKMT2ACYP1A2 | |
| SCHEMBL11188796 | 0.84 | NOX1 (0.46) | MEN1GAAMAPTKMT2ACYP1A2 | |
| SCHEMBL11181334 | 0.84 | MEN1 (0.41) | MEN1GAAMAPTKMT2ACYP1A2 | |
| SCHEMBL11187365 | 0.84 | GAA (0.41) | MEN1GAAMAPTKMT2ACYP1A2 | |
| SCHEMBL11193820 | 0.84 | GAA (0.41) | MEN1GAAMAPTKMT2ACYP1A2 | |
| SCHEMBL11181270 | 0.81 | GGT1 (0.50) | MEN1GAAMAPTKMT2ACYP1A2 | |
| SCHEMBL6545376 | 0.79 | GAA (0.44) | MEN1GAAMAPTKMT2ACYP1A2 | |
| SCHEMBL11186159 | 0.78 | NOX1 (0.40) | MEN1GAAMAPTKMT2ACYP1A2 | |
| SCHEMBL11189596 | 0.74 | L3MBTL1 (0.48) | MEN1GAAMAPTKMT2ACYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4399279-A | ANOREXIGENIC AGENTS | G.D. SEARLE & CO. (US) | 1983-08-16 | — | — | US | disclosed |
| US-4356302-A | ANOREXIGENIC AGENTS | G. D. SEARLE & CO. (US) | 1982-10-26 | — | — | US | disclosed |