Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX5 | P09917 | 1/20 | 0.54 |
| ▸ | MAOB | P27338 | 5/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.42 |
| ▸ | GPR35 | Q9HC97 | 2/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.42 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.42 |
| ▸ | CA1 | P00915 | 2/20 | 0.41 |
| ▸ | CA2 | P00918 | 2/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | CA12 | O43570 | 1/20 | 0.41 |
| ▸ | CA9 | Q16790 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.41 |
| ▸ | APP | P05067 | 1/20 | 0.40 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | NPC1 | O15118 | 2/20 | 0.40 |
| ▸ | RAB9A | P51151 | 2/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12248487 | 0.85 | ALOX5 (0.56) | ALOX5MAOBKDM4EGPR35ALDH1A1 | |
| SCHEMBL20559684 | 0.81 | ALOX5 (0.57) | ALOX5MAOBKDM4EGPR35ALDH1A1 | |
| SCHEMBL10459871 | 0.81 | ALOX5 (0.57) | ALOX5MAOBKDM4EGPR35ALDH1A1 | |
| Hydrochloric Acid SCHEMBL10458742 | 0.80 | ALOX5 (0.56) | ALOX5MAOBKDM4EGPR35ALDH1A1 | |
| SCHEMBL3417161 | 0.79 | MAOB (0.50) | ALOX5MAOBKDM4EGPR35ALDH1A1 | |
| SCHEMBL24352389 | 0.76 | TSHR (0.49) | ALOX5MAOBKDM4EGPR35ALDH1A1 | |
| SCHEMBL17785118 | 0.75 | CYP2D6 (0.49) | MAOBKDM4EALDH1A1CYP1A2CYP2C9 | |
| SCHEMBL12087021 | 0.74 | ALOX5 (0.50) | ALOX5MAOBKDM4EGPR35ALDH1A1 | |
| SCHEMBL28321258 | 0.74 | CYP2A6 (0.46) | ALOX5GPR35CA1CA2CYP19A1 | |
| SCHEMBL23258013 | 0.74 | ALOX5 (0.50) | ALOX5MAOBKDM4EGPR35ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4402968-A | Antifungal benzofuranyl imidazole compounds | HOFFMANN-LA ROCHE INC. (US) | 1983-09-06 | — | — | US | disclosed |