Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOB | P27338 | 4/20 | 0.50 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.44 |
| ▸ | GPR35 | Q9HC97 | 2/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.44 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.44 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.44 |
| ▸ | CA1 | P00915 | 2/20 | 0.43 |
| ▸ | CA2 | P00918 | 2/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.43 |
| ▸ | CA12 | O43570 | 1/20 | 0.43 |
| ▸ | CA9 | Q16790 | 1/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.39 |
| ▸ | NPC1 | O15118 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.39 |
| ▸ | APP | P05067 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3721824 | 0.83 | CYP2A6 (0.57) | GPR35ALDH1A1CA1CA2KMT2A | |
| SCHEMBL2043200 | 0.79 | CYP2A6 (0.52) | MAOBKDM4EGPR35ALDH1A1CA1 | |
| SCHEMBL11190837 | 0.79 | ALOX5 (0.54) | MAOBALOX5KDM4EGPR35ALDH1A1 | |
| SCHEMBL17541032 | 0.78 | CYP2A6 (0.50) | MAOBKDM4EALDH1A1CA1CA2 | |
| SCHEMBL12248487 | 0.74 | ALOX5 (0.56) | MAOBALOX5KDM4EGPR35ALDH1A1 | |
| SCHEMBL120463 | 0.73 | CYP2A6 (0.62) | MAOBALOX5KDM4EGPR35ALDH1A1 | |
| SCHEMBL28518711 | 0.72 | GPR35 (0.51) | MAOBALOX5KDM4EGPR35ALDH1A1 | |
| SCHEMBL20559684 | 0.71 | ALOX5 (0.57) | MAOBALOX5KDM4EGPR35ALDH1A1 | |
| SCHEMBL10459871 | 0.71 | ALOX5 (0.57) | MAOBALOX5KDM4EGPR35ALDH1A1 | |
| SCHEMBL11346189 | 0.71 | ALOX5 (0.57) | MAOBALOX5KDM4EGPR35ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2265606-A1 | HEPATITIS C VIRUS INHIBITORS | Bristol-Myers Squibb Company (US) | 2010-12-29 | — | — | EP | disclosed |
| WO-2009129109-A1 | HEPATITIS C VIRUS INHIBITORS | BRISTOL-MYERS SQUIBB COMPANY (US) | 2009-10-22 | — | — | WO | disclosed |