Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7902477 | 0.81 | CA2 (0.39) | LMNAALDH1A1SMN1; SMN2 | |
| SCHEMBL11185988 | 0.80 | LMNA (0.31) | LMNAALDH1A1 | |
| SCHEMBL4881453 | 0.80 | ALDH1A1 (0.42) | LMNAALDH1A1SMN1; SMN2 | |
| SCHEMBL9659860 | 0.77 | — | — | |
| SCHEMBL29077194 | 0.77 | ZDHHC7 (0.38) | LMNA | |
| SCHEMBL9202044 | 0.74 | — | — | |
| SCHEMBL1053416 | 0.73 | ALDH1A1 (0.36) | LMNAALDH1A1SMN1; SMN2 | |
| SCHEMBL25134015 | 0.71 | — | — | |
| SCHEMBL212936 | 0.71 | — | — | |
| SCHEMBL15922644 | 0.71 | ALDH1A1 (0.35) | LMNAALDH1A1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0011057-B1 | PROCESS FOR THE PREPARATION OF VINCADIFFORMINE AND DERIVATIVES THEREOF, INTERMEDIATES OBTAINED DURING THIS PROCESS AND PROCESS FOR THEIR PREPARATION | OMNICHEM Société anonyme (BE) | 1983-02-09 | — | — | EP | disclosed |
| US-4283536-A | Preparation of vincadifformine and related derivatives | UNIVERSITY OF VERMONT (US) | 1981-08-11 | — | — | US | disclosed |
| US-4267330-A | CONDENSATION OF A HALO-, SULFOAKLOXY-, OR OPOXYALDEHYDE WITH A DIALKYL 1,2,3,4,5,6-HEXAHYDROAZEPINO/4,5-B/INDOLE-5,5-DICARBOXYLATE; ALKALOIDS | OMNIUM CHIMIQUE SOCIETE ANONYME (BE) | 1981-05-12 | — | — | US | disclosed |
| EP-0011057-A1 | Process for the preparation of vincadifformine and derivatives thereof, intermediates obtained during this process and process for their preparation | OMNICHEM Société anonyme (BE) | 1980-05-14 | — | — | EP | disclosed |
| US-4154943-A | Preparation of vincadifformine | UNIVERSITY OF VERMONT (US) | 1979-05-15 | — | — | US | disclosed |