Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TRPV1 | Q8NER1 | 8/20 | 0.61 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.58 |
| ▸ | NPC1 | O15118 | 1/20 | 0.54 |
| ▸ | GALR3 | O60755 | 1/20 | 0.54 |
| ▸ | RAB9A | P51151 | 1/20 | 0.54 |
| ▸ | PLK1 | P53350 | 2/20 | 0.54 |
| ▸ | MAPT | P10636 | 1/20 | 0.51 |
| ▸ | CA12 | O43570 | 2/20 | 0.49 |
| ▸ | CA1 | P00915 | 2/20 | 0.49 |
| ▸ | CA2 | P00918 | 2/20 | 0.49 |
| ▸ | CA9 | Q16790 | 2/20 | 0.49 |
| ▸ | CCR5 | P51681 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11192040 | 0.96 | TRPV1 (0.56) | TRPV1KDM4ENPC1GALR3RAB9A | |
| SCHEMBL11188309 | 0.95 | PLK1 (0.56) | TRPV1KDM4EPLK1 | |
| SCHEMBL11191757 | 0.92 | TRPV1 (0.52) | TRPV1KDM4ENPC1RAB9APLK1 | |
| SCHEMBL11191768 | 0.87 | RAB9A (0.55) | TRPV1KDM4ENPC1RAB9APLK1 | |
| SCHEMBL6580185 | 0.85 | TRPV1 (0.61) | TRPV1KDM4ENPC1GALR3RAB9A | |
| SCHEMBL10112878 | 0.82 | TRPV1 (0.74) | TRPV1KDM4ENPC1GALR3RAB9A | |
| SCHEMBL10803698 | 0.82 | TRPV1 (0.74) | TRPV1KDM4ENPC1GALR3RAB9A | |
| SCHEMBL8756485 | 0.81 | PLK1 (0.57) | TRPV1PLK1 | |
| SCHEMBL11192829 | 0.79 | NPC1 (0.64) | KDM4ENPC1RAB9AMAPTCCR5 | |
| SCHEMBL2915657 | 0.79 | TRPV1 (0.72) | TRPV1KDM4ENPC1GALR3RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0083204-A2 | 2-Aminophenol derivatives and process for their preparation | ONO PHARMACEUTICAL CO., LTD. (JP) | 1983-07-06 | — | — | EP | disclosed |