Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TRPV1 | Q8NER1 | 8/20 | 0.61 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.58 |
| ▸ | NPC1 | O15118 | 1/20 | 0.54 |
| ▸ | GALR3 | O60755 | 1/20 | 0.54 |
| ▸ | RAB9A | P51151 | 1/20 | 0.54 |
| ▸ | PLK1 | P53350 | 3/20 | 0.54 |
| ▸ | MAPT | P10636 | 1/20 | 0.51 |
| ▸ | POLB | P06746 | 1/20 | 0.50 |
| ▸ | CCR5 | P51681 | 1/20 | 0.49 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6581728 | 0.89 | ALOX15 (0.57) | TRPV1NPC1RAB9APLK1POLB | |
| SCHEMBL6577799 | 0.89 | ALOX15 (0.57) | TRPV1KDM4ENPC1RAB9APOLB | |
| SCHEMBL6581908 | 0.87 | NPC1 (0.56) | TRPV1NPC1RAB9APLK1MAPT | |
| SCHEMBL11190894 | 0.85 | TRPV1 (0.61) | TRPV1KDM4ENPC1GALR3RAB9A | |
| SCHEMBL4326686 | 0.84 | TRPV1 (0.76) | TRPV1KDM4ENPC1GALR3RAB9A | |
| SCHEMBL6579798 | 0.84 | NR1H4 (0.61) | KDM4ENPC1RAB9AMAPT | |
| SCHEMBL11192040 | 0.81 | TRPV1 (0.56) | TRPV1KDM4ENPC1GALR3RAB9A | |
| SCHEMBL8756485 | 0.81 | PLK1 (0.57) | TRPV1PLK1 | |
| SCHEMBL1415882 | 0.80 | KAT8 (0.67) | TRPV1NPC1RAB9AMAPTALOX15 | |
| SCHEMBL11188309 | 0.80 | PLK1 (0.56) | TRPV1KDM4EPLK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0716088-B1 | PROCESS FOR PRODUCING 2-(TETRAZOL-5-YL)-4-OXO-4H-BENZOPYRANS | SUMITOMO CHEMICAL CO (JP) | 2004-02-18 | — | — | EP | disclosed |
| US-5597929-A | Production process of 2-(tetrazol-5-yl)-4-oxo-4H-benzopyran | SUMITOMO CHEMICAL CO., LTD. (JP) | 1997-01-28 | — | — | US | disclosed |
| EP-0716088-A1 | PROCESS FOR PRODUCING 2-(TETRAZOL-5-YL)-4-OXO-4H-BENZOPYRANS | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 1996-06-12 | — | — | EP | disclosed |