Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 10/20 | 0.64 |
| ▸ | RAB9A | P51151 | 10/20 | 0.64 |
| ▸ | MAPT | P10636 | 6/20 | 0.55 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.55 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.55 |
| ▸ | NFKB1 | P19838 | 2/20 | 0.55 |
| ▸ | NFKB2 | Q00653 | 2/20 | 0.55 |
| ▸ | RELA | Q04206 | 2/20 | 0.55 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.55 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.55 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.55 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.55 |
| ▸ | HPGD | P15428 | 1/20 | 0.55 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.55 |
| ▸ | KLK7 | P49862 | 1/20 | 0.55 |
| ▸ | MEN1 | O00255 | 4/20 | 0.54 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.54 |
| ▸ | POLB | P06746 | 4/20 | 0.54 |
| ▸ | TP53 | P04637 | 1/20 | 0.54 |
| ▸ | CCR5 | P51681 | 1/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28307210 | 0.87 | TOP1 (0.62) | NPC1RAB9AMAPTKDM4EMEN1 | |
| SCHEMBL15846834 | 0.86 | NPC1 (0.66) | NPC1RAB9AMAPTSMN1; SMN2ALDH1A1 | |
| SCHEMBL11195964 | 0.85 | MEN1 (0.59) | NPC1RAB9AMAPTSMN1; SMN2ALDH1A1 | |
| SCHEMBL11193981 | 0.84 | TP53 (0.63) | NPC1RAB9AMAPTSMN1; SMN2MEN1 | |
| SCHEMBL11196144 | 0.84 | SNCA (0.63) | NPC1RAB9ASMN1; SMN2NFKB1NFKB2 | |
| SCHEMBL11192743 | 0.84 | TRPV1 (0.53) | NPC1RAB9AMAPTMEN1KMT2A | |
| SCHEMBL11191641 | 0.84 | NPC1 (0.57) | NPC1RAB9AMAPTSMN1; SMN2ALDH1A1 | |
| SCHEMBL11202607 | 0.84 | KMT2A (0.62) | NPC1RAB9AMAPTSMN1; SMN2KDM4E | |
| SCHEMBL13593263 | 0.84 | TOP1 (0.74) | NPC1RAB9AMAPTKDM4EMEN1 | |
| SCHEMBL11191768 | 0.84 | RAB9A (0.55) | NPC1RAB9AMAPTSMN1; SMN2ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0083204-A2 | 2-Aminophenol derivatives and process for their preparation | ONO PHARMACEUTICAL CO., LTD. (JP) | 1983-07-06 | — | — | EP | disclosed |