Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.78 |
| ▸ | SMN1; SMN2 | Q16637 | 6/20 | 0.78 |
| ▸ | MEN1 | O00255 | 2/20 | 0.78 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.78 |
| ▸ | RAB9A | P51151 | 5/20 | 0.72 |
| ▸ | MAPT | P10636 | 3/20 | 0.72 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.72 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.72 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.72 |
| ▸ | HPGD | P15428 | 2/20 | 0.72 |
| ▸ | CA1 | P00915 | 1/20 | 0.69 |
| ▸ | CA2 | P00918 | 1/20 | 0.69 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.68 |
| ▸ | NPC1 | O15118 | 2/20 | 0.68 |
| ▸ | LMNA | P02545 | 1/20 | 0.67 |
| ▸ | HTT | P42858 | 1/20 | 0.67 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.67 |
| ▸ | GAA | P10253 | 1/20 | 0.66 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11667197 | 0.88 | HTT (0.76) | ALDH1A1SMN1; SMN2MEN1KMT2ARAB9A | |
| SCHEMBL9859901 | 0.86 | SMN1; SMN2 (0.67) | ALDH1A1SMN1; SMN2MEN1KMT2ARAB9A | |
| SCHEMBL11643864 | 0.84 | ALDH1A1 (0.70) | ALDH1A1SMN1; SMN2MEN1KMT2ARAB9A | |
| SCHEMBL11647735 | 0.84 | ALDH1A1 (1.00) | ALDH1A1SMN1; SMN2MEN1KMT2ARAB9A | |
| SCHEMBL7845148 | 0.84 | SMN1; SMN2 (0.80) | ALDH1A1SMN1; SMN2KMT2ARAB9AMAPT | |
| SCHEMBL11719425 | 0.83 | ALDH1A1 (0.70) | ALDH1A1SMN1; SMN2MEN1KMT2ARAB9A | |
| SCHEMBL11645917 | 0.82 | KMT2A (0.67) | ALDH1A1SMN1; SMN2MEN1KMT2ARAB9A | |
| SCHEMBL11646615 | 0.81 | ALDH1A1 (1.00) | ALDH1A1SMN1; SMN2MEN1KMT2ARAB9A | |
| SCHEMBL11338235 | 0.81 | SMN1; SMN2 (0.70) | ALDH1A1SMN1; SMN2MEN1KMT2ARAB9A | |
| SCHEMBL11618998 | 0.81 | RAB9A (1.00) | SMN1; SMN2MEN1KMT2ARAB9AMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4419516-A | Antiviral imidazo- and triazolo-pyridines | AMERICAN HOME PRODUCTS CORPORATION (US) | 1983-12-06 | — | — | US | disclosed |