Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.80 |
| ▸ | HTT | P42858 | 1/20 | 0.80 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.74 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.74 |
| ▸ | LMNA | P02545 | 2/20 | 0.74 |
| ▸ | MAPT | P10636 | 4/20 | 0.73 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.73 |
| ▸ | CA1 | P00915 | 1/20 | 0.70 |
| ▸ | CA2 | P00918 | 1/20 | 0.70 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.70 |
| ▸ | GAA | P10253 | 1/20 | 0.69 |
| ▸ | RAB9A | P51151 | 2/20 | 0.63 |
| ▸ | NPC1 | O15118 | 1/20 | 0.62 |
| ▸ | MAOA | P21397 | 1/20 | 0.62 |
| ▸ | MAOB | P27338 | 1/20 | 0.62 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18292385 | 0.85 | LMNA (1.00) | SMN1; SMN2HTTALDH1A1NPSR1LMNA | |
| SCHEMBL6951326 | 0.85 | ALDH1A1 (0.74) | SMN1; SMN2HTTALDH1A1NPSR1LMNA | |
| SCHEMBL14434237 | 0.85 | MAPT (1.00) | SMN1; SMN2HTTALDH1A1NPSR1LMNA | |
| SCHEMBL11190896 | 0.84 | ALDH1A1 (0.78) | SMN1; SMN2HTTALDH1A1NPSR1LMNA | |
| SCHEMBL5520981 | 0.84 | SMN1; SMN2 (0.70) | SMN1; SMN2HTTALDH1A1NPSR1LMNA | |
| SCHEMBL12049597 | 0.83 | RAB9A (0.69) | SMN1; SMN2HTTALDH1A1NPSR1LMNA | |
| SCHEMBL170487 | 0.82 | RAB9A (0.62) | SMN1; SMN2HTTALDH1A1NPSR1LMNA | |
| SCHEMBL7844957 | 0.82 | CNR1 (0.80) | SMN1; SMN2HTTLMNAMAPTKDM4E | |
| SCHEMBL6213313 | 0.81 | SMN1; SMN2 (0.62) | SMN1; SMN2HTTALDH1A1NPSR1LMNA | |
| SCHEMBL159773 | 0.80 | SMN1; SMN2 (0.60) | SMN1; SMN2HTTALDH1A1NPSR1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0718300-B1 | Carbodiimide derivative | NISSHIN SPINNING (JP) | 2001-11-21 | — | — | EP | disclosed |
| US-5789588-A | BIOTIN DERIVATIIVES OF CARBODIIMIDE FOR NUCLEIC ACIDS AND PROTEINS | NISSHINBO INDUSTRIES, INC. (JP) | 1998-08-04 | — | — | US | disclosed |
| US-5700935-A | LABEL FOR INTRODUCING BIOTIN GROUP INTO NUCLEIC ACID | NISSHINBO INDUSTRIES, INC. (JP) | 1997-12-23 | — | — | US | disclosed |
| EP-0718300-A1 | Carbodiimide derivative | NISSHINBO INDUSTRIES, INC. (JP) | 1996-06-26 | — | — | EP | disclosed |
| US-4112100-A | INCREASING THE ENDOGENOUS PRODUCTION OF PROSTAGLANDINS | THE UPJOHN COMPANY (US) | 1978-09-05 | — | — | US | disclosed |