Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA2 | P00918 | 2/20 | 0.49 |
| ▸ | CA1 | P00915 | 1/20 | 0.43 |
| ▸ | AHR | P35869 | 2/20 | 0.39 |
| ▸ | NPC1 | O15118 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
| ▸ | HTR1A | P08908 | 1/20 | 0.39 |
| ▸ | DRD2 | P14416 | 1/20 | 0.39 |
| ▸ | DRD4 | P21917 | 1/20 | 0.39 |
| ▸ | ADRA1D | P25100 | 1/20 | 0.39 |
| ▸ | HTR2C | P28335 | 1/20 | 0.39 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.39 |
| ▸ | ADRA1B | P35368 | 1/20 | 0.39 |
| ▸ | DRD3 | P35462 | 1/20 | 0.39 |
| ▸ | FFAR1 | O14842 | 8/20 | 0.37 |
| ▸ | HTT | P42858 | 1/20 | 0.37 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.37 |
| ▸ | MAOB | P27338 | 1/20 | 0.36 |
| ▸ | MAP3K14 | Q99558 | 1/20 | 0.36 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.35 |
| ▸ | CYP2B6 | P20813 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1119127 | 1.00 | CA2 (0.49) | CA2CA1AHRNPC1L3MBTL1 | |
| SCHEMBL1119149 | 0.93 | CA2 (0.49) | CA2CA1AHRNPC1L3MBTL1 | |
| SCHEMBL1119152 | 0.93 | CA2 (0.49) | CA2CA1AHRNPC1L3MBTL1 | |
| SCHEMBL1877576 | 0.79 | CA2 (0.48) | CA2CA1AHRNPC1L3MBTL1 | |
| SCHEMBL4962751 | 0.78 | CA2 (0.33) | CA2CA1NPC1L3MBTL1HTT | |
| SCHEMBL6761876 | 0.78 | CA2 (0.65) | CA2CA1NPC1HTR1ADRD2 | |
| SCHEMBL4961667 | 0.77 | AQP1 (0.41) | CA2CA1NPC1L3MBTL1HTR2C | |
| SCHEMBL4960250 | 0.76 | NPC1 (0.39) | CA2CA1NPC1L3MBTL1HTT | |
| SCHEMBL4960249 | 0.76 | NPC1 (0.39) | CA2CA1NPC1L3MBTL1HTT | |
| SCHEMBL3809469 | 0.76 | POLB (0.46) | CA2NPC1L3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2280951-A2 | PROCESSES FOR THE PREPARATION OF BENZO-FUSED DIOXIN DERIVATIVES | Janssen Pharmaceutica, N.V. (BE) | 2011-02-09 | — | — | EP | disclosed |
| WO-2009120192-A2 | PROCESS FOR THE PREPARATION OF BENZO-FUSED HETEROARYL DERIVATIVES | JASSEN PHARMACEUTICA, N.V. (BE) | 2009-10-01 | — | — | WO | disclosed |
| US-20090247618-A1 | PROCESS FOR PREPARATION OF BENZO-FUSED HETEROARYL DERIVATIVES | JANSSEN PHARMACEUTICA, N.C. (BE) | 2009-10-01 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090247618-A1 | PROCESS FOR PREPARATION OF BENZO-FUSED HETEROARYL DERIVATIVES | CYP3A4, CYP3A5, CYP1A2 | CA2 3270/4885CA1 2909/4885AHR 213/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.