Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA2 | P00918 | 4/20 | 0.65 |
| ▸ | CA1 | P00915 | 1/20 | 0.58 |
| ▸ | HTR6 | P50406 | 1/20 | 0.57 |
| ▸ | DRD2 | P14416 | 3/20 | 0.51 |
| ▸ | DRD4 | P21917 | 3/20 | 0.51 |
| ▸ | DRD3 | P35462 | 3/20 | 0.51 |
| ▸ | HTR1A | P08908 | 1/20 | 0.51 |
| ▸ | ADRA1D | P25100 | 1/20 | 0.51 |
| ▸ | HTR2C | P28335 | 1/20 | 0.51 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.51 |
| ▸ | ADRA1B | P35368 | 1/20 | 0.51 |
| ▸ | FFAR1 | O14842 | 7/20 | 0.49 |
| ▸ | NPC1 | O15118 | 1/20 | 0.47 |
| ▸ | TSHR | P16473 | 1/20 | 0.47 |
| ▸ | RAB9A | P51151 | 1/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.47 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.43 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.43 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9120130 | 0.94 | CA2 (0.65) | CA2CA1HTR6DRD2DRD4 | |
| SCHEMBL16089590 | 0.83 | CA2 (0.58) | CA2CA1DRD2DRD4DRD3 | |
| SCHEMBL27749911 | 0.81 | CA2 (0.64) | CA2CA1HTR6DRD2DRD4 | |
| SCHEMBL11025999 | 0.81 | CA2 (0.59) | CA2CA1DRD2DRD4DRD3 | |
| SCHEMBL1044791 | 0.80 | CA2 (0.58) | CA2CA1DRD2DRD4DRD3 | |
| SCHEMBL4764921 | 0.80 | CA2 (0.62) | CA2CA1DRD2DRD4DRD3 | |
| SCHEMBL28709527 | 0.80 | CA2 (0.58) | CA2CA1DRD2DRD4DRD3 | |
| SCHEMBL1119121 | 0.80 | CA2 (0.58) | CA2CA1DRD2DRD4DRD3 | |
| SCHEMBL15864967 | 0.80 | CA2 (0.58) | CA2CA1DRD2DRD4DRD3 | |
| SCHEMBL29444759 | 0.80 | CA2 (0.58) | CA2CA1DRD2DRD4DRD3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20040039023-A1 | Therapeutic agents | KNOLL GMBH (DE) | 2004-02-26 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040039023-A1 | Therapeutic agents | AMY1A, PARK7, SNCA | CA2 2894/4885CA1 1180/4885HTR6 338/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.