Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.50 |
| ▸ | TP53 | P04637 | 1/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
| ▸ | POLB | P06746 | 2/20 | 0.43 |
| ▸ | CA12 | O43570 | 1/20 | 0.43 |
| ▸ | CA9 | Q16790 | 1/20 | 0.43 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.43 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.43 |
| ▸ | GLA | P06280 | 1/20 | 0.43 |
| ▸ | STING1 | Q86WV6 | 1/20 | 0.43 |
| ▸ | CFD | P00746 | 2/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
| ▸ | PTGER1 | P34995 | 1/20 | 0.42 |
| ▸ | PTGER4 | P35408 | 1/20 | 0.42 |
| ▸ | PTGER3 | P43115 | 1/20 | 0.42 |
| ▸ | PTGER2 | P43116 | 1/20 | 0.42 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.41 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.41 |
| ▸ | NPC1 | O15118 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Methane SCHEMBL3681148 | 0.98 | TDP1 (0.49) | TDP1TP53KDM4EPOLBCA12 | |
| SCHEMBL11706481 | 0.91 | TDP1 (0.44) | TDP1TP53KDM4EPOLBCA12 | |
| SCHEMBL11703638 | 0.89 | CA12 (0.46) | TDP1TP53KDM4EPOLBCA12 | |
| SCHEMBL11554183 | 0.89 | POLB (0.51) | TDP1KDM4EPOLBCA12CA9 | |
| SCHEMBL11705101 | 0.88 | ACACA (0.44) | TDP1TP53KDM4EPOLBCA12 | |
| SCHEMBL11703313 | 0.86 | KMT2A (0.45) | TP53KDM4EPOLBSMN1; SMN2PTGER4 | |
| SCHEMBL11705295 | 0.85 | PDCD1 (0.49) | KDM4EPOLBSMN1; SMN2ALOX15ALOX12 | |
| SCHEMBL11700505 | 0.85 | RXRA (0.42) | TDP1TP53POLBCA12CA9 | |
| SCHEMBL11702876 | 0.85 | MMP2 (0.51) | TDP1TP53KDM4ESMN1; SMN2 | |
| SCHEMBL11703057 | 0.85 | FFAR1 (0.42) | TDP1TP53POLBCA12CA9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4013692-A | ANTIINFLAMMATORY, ANTIPYRETICS, ANALGESICS | RIKER LABORATORIES, INC. (US) | 1977-03-22 | — | — | US | claimed |
| US-4391814-A | Derivatives of antiphlogistically effective carboxylic acids, their preparation and medicinal use | SCHERING AKTIENGESELLSCHAFT (DE) | 1983-07-05 | — | — | US | disclosed |
| EP-0054812-A1 | Derivatives of antiphlogistically active carboxylic acids, their preparation and medical application | SCHERING AKTIENGESELLSCHAFT (DE) | 1982-06-30 | — | — | EP | disclosed |
| US-4153619-A | MICROBIOCIDES | RIKER LABORATORIES, INC. (US) | 1979-05-08 | — | — | US | disclosed |
| US-4124704-A | ANTIMICROBIAL | RIKER LABORATORIES, INC. (US) | 1978-11-07 | — | — | US | disclosed |
| US-4013692-A | ANTIINFLAMMATORY, ANTIPYRETICS, ANALGESICS | RIKER LABORATORIES, INC. (US) | 1977-03-22 | — | — | US | disclosed |