Predicted protein targets (top 2)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACE | P12821 | 11/20 | 0.38 |
| ▸ | FFAR2 | O15552 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11061433 | 0.80 | HSD17B10 (0.49) | ACEFFAR2 | |
| SCHEMBL11066109 | 0.77 | ACE (0.63) | ACEFFAR2 | |
| SCHEMBL10938811 | 0.77 | ACE (0.63) | ACEFFAR2 | |
| SCHEMBL11067693 | 0.76 | ACE (0.41) | ACEFFAR2 | |
| SCHEMBL11304547 | 0.74 | SLC18A3 (0.37) | ACE | |
| SCHEMBL11110323 | 0.73 | FFAR2 (0.47) | ACEFFAR2 | |
| SCHEMBL10995336 | 0.71 | FFAR2 (0.43) | ACEFFAR2 | |
| SCHEMBL10968292 | 0.71 | ACE (0.64) | ACEFFAR2 | |
| SCHEMBL10999348 | 0.68 | ACE (0.47) | ACEFFAR2 | |
| SCHEMBL11090000 | 0.67 | FFAR2 (0.44) | ACEFFAR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4423054-A | Antihypertensive 4-thiazolidinecarboxylic acids (substituted alkyl derivatives) | SANTEN PHARMACEUTICAL CO., LTD. (JP) | 1983-12-27 | — | — | US | claimed |