Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PAX8 | Q06710 | 1/20 | 0.42 |
| ▸ | DPP4 | P27487 | 2/20 | 0.41 |
| ▸ | CTRB1 | P17538 | 5/20 | 0.39 |
| ▸ | DPP8 | Q6V1X1 | 2/20 | 0.37 |
| ▸ | DPP7 | Q9UHL4 | 1/20 | 0.37 |
| ▸ | DPP9 | Q86TI2 | 1/20 | 0.33 |
| ▸ | MME | P08473 | 2/20 | 0.33 |
| ▸ | SLC15A1 | P46059 | 1/20 | 0.33 |
| ▸ | CACNA2D1 | P54289 | 2/20 | 0.32 |
| ▸ | GABRP | O00591 | 2/20 | 0.32 |
| ▸ | GABRD | O14764 | 2/20 | 0.32 |
| ▸ | GABRA1 | P14867 | 2/20 | 0.32 |
| ▸ | GABRB1 | P18505 | 2/20 | 0.32 |
| ▸ | GABRG2 | P18507 | 2/20 | 0.32 |
| ▸ | GABRB3 | P28472 | 2/20 | 0.32 |
| ▸ | GABRA5 | P31644 | 2/20 | 0.32 |
| ▸ | GABRA3 | P34903 | 2/20 | 0.32 |
| ▸ | GABRA2 | P47869 | 2/20 | 0.32 |
| ▸ | GABRB2 | P47870 | 2/20 | 0.32 |
| ▸ | GABRA4 | P48169 | 2/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11232274 | 0.82 | GABRP (0.47) | PAX8DPP4CTRB1DPP8DPP7 | |
| SCHEMBL11192511 | 0.78 | DPP4 (0.41) | PAX8DPP4CTRB1DPP8DPP7 | |
| SCHEMBL4010222 | 0.77 | PAX8 (0.40) | PAX8DPP4DPP8DPP7MME | |
| SCHEMBL4012013 | 0.77 | PAX8 (0.40) | PAX8DPP4DPP8DPP7MME | |
| SCHEMBL4014184 | 0.77 | PAX8 (0.40) | PAX8DPP4DPP8DPP7MME | |
| SCHEMBL4011326 | 0.77 | PAX8 (0.40) | PAX8DPP4DPP8DPP7MME | |
| SCHEMBL11191528 | 0.76 | SMN1; SMN2 (0.38) | CTRB1 | |
| SCHEMBL18776186 | 0.76 | DPP4 (0.47) | PAX8DPP4CTRB1DPP8DPP7 | |
| SCHEMBL4005620 | 0.75 | DPP8 (0.42) | PAX8DPP4CTRB1DPP8DPP7 | |
| SCHEMBL4015003 | 0.75 | DPP8 (0.42) | PAX8DPP4CTRB1DPP8DPP7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0024965-B1 | FLUORINATED METHYL BETA-ALANINE DERIVATIVES, THEIR PREPARATION AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM | MERRELL TORAUDE ET COMPAGNIE (FR) | 1983-04-27 | — | — | EP | disclosed |
| US-4375477-A | ENZYME INHIBITORS | MERRELL TORAUDE ET COMPAGNIE (FR) | 1983-03-01 | — | — | US | disclosed |
| EP-0024965-A1 | Fluorinated methyl beta-alanine derivatives, their preparation and pharmaceutical compositions containing them | MERRELL TORAUDE ET COMPAGNIE (FR) | 1981-03-11 | — | — | EP | disclosed |