SCHEMBL11196340

SCHEMBL11196340

C#CCc1ccc(CBr)cc1

nearest known ligand 0.43

Predicted protein targets (top 7)

geneUniProtsupporting neighboursconfidence
TRPA1 O75762 1/20 0.43
ALDH1A1 P00352 1/20 0.43
TSHR P16473 1/20 0.43
PYCR1 P32322 5/20 0.39
CES2 O00748 1/20 0.35
CES1 P23141 1/20 0.35
MAOB P27338 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL18770738 0.79 PYCR1 (0.54) PYCR1MAOB
SCHEMBL131361 0.76 ALDH1A1 (0.67) TRPA1ALDH1A1TSHRCES2CES1
SCHEMBL200320 0.74 TRPA1 (0.43) TRPA1ALDH1A1TSHRCES2CES1
SCHEMBL7069164 0.74 TSHR (0.43) TRPA1ALDH1A1TSHRCES2CES1
SCHEMBL357871 0.74 ESR1 (0.50) TRPA1ALDH1A1MAOB
SCHEMBL1253137 0.74 TRPA1 (0.43) TRPA1ALDH1A1TSHRPYCR1CES2
SCHEMBL11193453 0.74 PYCR1 (0.30) PYCR1
SCHEMBL1921131 0.74 PYCR1 (0.50) ALDH1A1PYCR1MAOB
SCHEMBL5249523 0.74 PYCR1 (0.52) ALDH1A1PYCR1MAOB
SCHEMBL186500 0.74 PYCR1 (0.50) PYCR1MAOB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-4411912-A Insecticidal isovaleric acid esters ZOECON CORPORATION (US) 1983-10-25 US disclosed
US-4243819-A Substituted amino acids ZOECON CORPORATION (US) 1981-01-06 US disclosed