SCHEMBL1119643

SCHEMBL1119643

O=C(O)C1(O)C=CC(c2ccccc2)C=C1

nearest known ligand 0.35

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
THRB P10828 1/20 0.35
TDP1 Q9NUW8 1/20 0.35
EDNRA P25101 1/20 0.34
HDAC4 P56524 4/20 0.33
MAPK1 P28482 1/20 0.33
CYP2C19 P33261 1/20 0.33
HDAC3 O15379 1/20 0.33
HDAC7 Q8WUI4 1/20 0.33
HDAC8 Q9BY41 1/20 0.33
HDAC6 Q9UBN7 1/20 0.33
HDAC9 Q9UKV0 1/20 0.33
HDAC5 Q9UQL6 1/20 0.33
CA2 P00918 1/20 0.32
EPHX1 P07099 1/20 0.32
OPRK1 P41145 1/20 0.32
CHRNA7 P36544 1/20 0.32
AKR1C3 P42330 1/20 0.32
AKR1C1 Q04828 1/20 0.32
POLB P06746 1/20 0.32
KDM1A O60341 3/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL316145 0.82 EDNRA (0.35) THRBTDP1EDNRAHDAC4MAPK1
SCHEMBL8970777 0.80 MAPT (0.43) EDNRAPOLB
SCHEMBL222998 0.79 CHRNA7 (0.35) EDNRACYP2C19CA2CHRNA7KDM1A
SCHEMBL3583056 0.78 GRM1 (0.35) EDNRAHDAC4MAPK1CYP2C19HDAC3
SCHEMBL4371618 0.78 SLC9A1 (0.36) EDNRAMAPK1CYP2C19OPRK1CHRNA7
SCHEMBL2508140 0.78 HTR2A (0.35) THRBTDP1EDNRAHDAC4MAPK1
SCHEMBL6601729 0.78 HTR2A (0.35) THRBTDP1EDNRAHDAC4MAPK1
SCHEMBL2121106 0.78 KDM1A (0.34) EDNRAHDAC4MAPK1CYP2C19HDAC3
SCHEMBL6709305 0.78 EDNRA (0.34) EDNRAHDAC4MAPK1CYP2C19HDAC3
SCHEMBL6851218 0.78 LMNA (0.47) POLB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 189 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-114805752-B Preparation method of heat-conducting liquid crystal epoxy resin 浙江亚厦装饰股份有限公司 2024-04-09 CN claimed
CN-115322352-B Preparation and application of liquid crystal polymer based on 6-hydroxy-2-naphthoic acid derivative 浙江羲和新材料科技有限公司 2023-08-25 CN claimed
CN-114805752-A Preparation method of heat-conducting liquid crystal epoxy resin 浙江亚厦装饰股份有限公司 2022-07-29 CN claimed
CN-114641291-A Compositions of small molecule therapeutic compounds 戴尔普尔有限公司 2022-06-17 CN claimed
CN-111303391-B Liquid crystal polymer containing fluorene and preparation method thereof 南京清研高分子新材料有限公司 2022-05-24 CN claimed
CN-114149573-A Fluorine-containing liquid crystal copolyester and finished low-dielectric liquid crystal polymer composition 惠生(中国)投资有限公司 2022-03-08 CN claimed
CN-112004538-A Compositions of small molecule therapeutic compounds 德尔宝股份有限公司 2020-11-27 CN claimed
CN-111849507-A Fluorine-containing liquid crystal molecule with cholesterol as chiral center and preparation method thereof 智谱纳米科技(上海)有限公司 2020-10-30 CN claimed
CN-111303391-A Liquid crystal polymer containing fluorene and preparation method thereof 南京清研高分子新材料有限公司 2020-06-19 CN claimed
US-9260742-B2 Methods for detecting organisms and enzymatic reactions using raman spectroscopy SWORD DIAGNOSTICS, INC. (IN) 2016-02-16 US claimed
EP-1137391-A1 METHOD FOR TREATING HAIR Novozymes A/S (DK) 2001-10-04 EP claimed
WO-2001068042-A1 METHOD FOR DYEING DRY HAIR NOVOZYMES A/S (DK) 2001-09-20 WO claimed
EP-1076494-A1 RE-FORMATION OF KERATINOUS FIBRE CROSS LINKS Novozymes A/S (DK) 2001-02-21 EP claimed
WO-2000039263-A1 PLEUROTUS PHENOL OXIDIZING ENZYMES GENENCOR INTERNATIONAL, INC. (US) 2000-07-06 WO claimed
WO-2000037601-A2 PLEUROTUS PHENOL OXIDIZING ENZYMES GENENCOR INTERNATIONAL, INC. (US) 2000-06-29 WO claimed
WO-2000032158-A1 METHOD FOR TREATING HAIR NOVOZYMES A/S (DK) 2000-06-08 WO claimed
WO-1999058013-A1 RE-FORMATION OF KERATINOUS FIBRE CROSS LINKS NOVO NORDISK A/S (DK) 1999-11-18 WO claimed
EP-0866988-A1 POLARIZER FILMS COMPRISING WHOLLY AROMATIC LIQUID CRYSTALLINE POLYMERS AND DICHROIC DYES HOECHST CELANESE CORPORATION (US) 1998-09-30 EP claimed
WO-1997023790-A1 POLARIZER FILMS COMPRISING WHOLLY AROMATIC LIQUID CRYSTALLINE POLYMERS AND DICHROIC DYES HOECHST CELANESE CORPORATION (US) 1997-07-03 WO claimed
WO-1997019374-A1 POLARIZER FILMS COMPRISING AROMATIC LIQUID CRYSTALLINE POLYMERS COMPRISING DICHROIC DYES IN THEIR MAIN CHAINS HOECHST CELANESE CORPORATION (US) 1997-05-29 WO claimed