Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CACNA1C | Q13936 | 3/20 | 0.39 |
| ▸ | ACHE | P22303 | 2/20 | 0.39 |
| ▸ | CACNA1F | O60840 | 2/20 | 0.39 |
| ▸ | CACNA1D | Q01668 | 2/20 | 0.39 |
| ▸ | CACNA1S | Q13698 | 2/20 | 0.39 |
| ▸ | CACNA1H | O95180 | 2/20 | 0.39 |
| ▸ | CACNA1B | Q00975 | 2/20 | 0.39 |
| ▸ | CACNB4 | O00305 | 1/20 | 0.39 |
| ▸ | CACNA1A | O00555 | 1/20 | 0.39 |
| ▸ | CACNA1G | O43497 | 1/20 | 0.39 |
| ▸ | CACNG3 | O60359 | 1/20 | 0.39 |
| ▸ | BCHE | P06276 | 1/20 | 0.39 |
| ▸ | CACNB3 | P54284 | 1/20 | 0.39 |
| ▸ | CACNA2D1 | P54289 | 1/20 | 0.39 |
| ▸ | CACNG7 | P62955 | 1/20 | 0.39 |
| ▸ | CACNB1 | Q02641 | 1/20 | 0.39 |
| ▸ | CACNG1 | Q06432 | 1/20 | 0.39 |
| ▸ | CACNB2 | Q08289 | 1/20 | 0.39 |
| ▸ | CACNA1E | Q15878 | 1/20 | 0.39 |
| ▸ | CACNA2D4 | Q7Z3S7 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10914189 | 0.92 | ACHE (0.39) | CACNA1CACHECACNA1FCACNA1DCACNA1S | |
| SCHEMBL10921450 | 0.89 | ALDH1A1 (0.44) | CACNA1CACHECACNA1FCACNA1DCACNA1S | |
| SCHEMBL10921757 | 0.86 | KMT2A (0.47) | CACNA1CACHECACNA1FCACNA1DCACNA1S | |
| SCHEMBL11006831 | 0.86 | ACHE (0.49) | CACNA1CACHECACNA1FCACNA1DCACNA1S | |
| SCHEMBL10970619 | 0.85 | ALDH1A1 (0.38) | CACNA1CACHECACNA1FCACNA1DCACNA1S | |
| SCHEMBL10924991 | 0.83 | KMT2A (0.44) | CACNA1CACHECACNA1FCACNA1DCACNA1S | |
| SCHEMBL10915340 | 0.81 | MEN1 (0.52) | CACNA1CACHECACNA1FCACNA1DCACNA1S | |
| SCHEMBL11009673 | 0.78 | ALDH1A1 (0.55) | CACNA1CACHECACNA1FCACNA1DCACNA1S | |
| SCHEMBL10744670 | 0.78 | ACHE (0.49) | CACNA1CACHECACNA1FCACNA1DCACNA1S | |
| SCHEMBL10923467 | 0.77 | ALDH1A1 (0.44) | CACNA1CACHECACNA1FCACNA1DCACNA1S |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0088938-A1 | Use of pyridine compounds for the manufacture of medicaments with an antihypoxemia and ischemia-protective activity | BAYER AG (DE) | 1983-09-21 | — | — | EP | disclosed |
| EP-0088940-A1 | Pyridine-carboxylic-acid esters, process for their preparation and their use as pharmaceutical compositions | BAYER AG (DE) | 1983-09-21 | — | — | EP | disclosed |