Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.38 |
| ▸ | PKM | P14618 | 1/20 | 0.38 |
| ▸ | AKR1C3 | P42330 | 3/20 | 0.38 |
| ▸ | AKR1C2 | P52895 | 3/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | ACHE | P22303 | 2/20 | 0.37 |
| ▸ | CACNA1C | Q13936 | 2/20 | 0.37 |
| ▸ | CACNB4 | O00305 | 1/20 | 0.37 |
| ▸ | CACNA1A | O00555 | 1/20 | 0.37 |
| ▸ | CACNA1G | O43497 | 1/20 | 0.37 |
| ▸ | CACNG3 | O60359 | 1/20 | 0.37 |
| ▸ | CACNA1F | O60840 | 1/20 | 0.37 |
| ▸ | CACNA1H | O95180 | 1/20 | 0.37 |
| ▸ | BCHE | P06276 | 1/20 | 0.37 |
| ▸ | CACNB3 | P54284 | 1/20 | 0.37 |
| ▸ | CACNA2D1 | P54289 | 1/20 | 0.37 |
| ▸ | CACNG7 | P62955 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10921450 | 0.92 | ALDH1A1 (0.44) | ALDH1A1PKMAKR1C3AKR1C2MEN1 | |
| SCHEMBL10920420 | 0.86 | ALDH1A1 (0.46) | ALDH1A1PKMAKR1C3AKR1C2MEN1 | |
| SCHEMBL10914189 | 0.86 | ACHE (0.39) | ALDH1A1PKMMEN1KMT2AACHE | |
| SCHEMBL11009475 | 0.85 | CACNA1C (0.45) | ALDH1A1PKMAKR1C3AKR1C2MEN1 | |
| SCHEMBL11197176 | 0.85 | CACNA1C (0.39) | ALDH1A1PKMMEN1KMT2ATDP1 | |
| SCHEMBL10924017 | 0.83 | AKR1C3 (0.45) | ALDH1A1PKMAKR1C3AKR1C2MEN1 | |
| SCHEMBL8803416 | 0.81 | SLC6A3 (0.38) | AKR1C3AKR1C2MEN1KMT2A | |
| SCHEMBL10924663 | 0.81 | MAPT (0.46) | ALDH1A1PKMMEN1KMT2ATDP1 | |
| SCHEMBL10911153 | 0.79 | ALDH1A1 (0.43) | ALDH1A1PKMAKR1C3AKR1C2MEN1 | |
| SCHEMBL10915211 | 0.79 | ALDH1A1 (0.43) | ALDH1A1PKMAKR1C3AKR1C2MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0088938-B1 | USE OF PYRIDINE COMPOUNDS FOR THE MANUFACTURE OF MEDICAMENTS WITH AN ANTIHYPOXEMIA AND ISCHEMIA-PROTECTIVE ACTIVITY | BAYER AG (DE) | 1986-04-30 | — | — | EP | disclosed |
| EP-0088938-A1 | Use of pyridine compounds for the manufacture of medicaments with an antihypoxemia and ischemia-protective activity | BAYER AG (DE) | 1983-09-21 | — | — | EP | disclosed |