Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.63 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.63 |
| ▸ | HPGD | P15428 | 1/20 | 0.63 |
| ▸ | MAOB | P27338 | 1/20 | 0.54 |
| ▸ | AOC3 | Q16853 | 1/20 | 0.54 |
| ▸ | TBXAS1 | P24557 | 1/20 | 0.50 |
| ▸ | DRD2 | P14416 | 1/20 | 0.44 |
| ▸ | GPR119 | Q8TDV5 | 6/20 | 0.44 |
| ▸ | ABL1 | P00519 | 1/20 | 0.44 |
| ▸ | EGFR | P00533 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 2/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.43 |
| ▸ | NPC1 | O15118 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | RAB9A | P51151 | 1/20 | 0.43 |
| ▸ | PARP10 | Q53GL7 | 1/20 | 0.42 |
| ▸ | GAA | P10253 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9388919 | 0.83 | ALDH1A1 (0.66) | ALDH1A1SMN1; SMN2HPGDMAOBAOC3 | |
| SCHEMBL578734 | 0.80 | ALDH1A1 (0.61) | ALDH1A1SMN1; SMN2HPGDMAOBAOC3 | |
| SCHEMBL10932269 | 0.80 | ALDH1A1 (0.61) | ALDH1A1SMN1; SMN2HPGDTBXAS1L3MBTL1 | |
| SCHEMBL10460818 | 0.79 | ALDH1A1 (0.59) | ALDH1A1SMN1; SMN2HPGDMAOBAOC3 | |
| SCHEMBL26681150 | 0.79 | ALDH1A1 (0.59) | ALDH1A1SMN1; SMN2HPGDMAOBAOC3 | |
| SCHEMBL10754241 | 0.79 | ALDH1A1 (0.59) | ALDH1A1SMN1; SMN2HPGDMAOBAOC3 | |
| SCHEMBL2535516 | 0.79 | HPGD (0.70) | ALDH1A1SMN1; SMN2HPGDMAOBAOC3 | |
| SCHEMBL7042102 | 0.79 | L3MBTL1 (0.68) | ALDH1A1SMN1; SMN2HPGDMAOBMAPT | |
| Hydrochloric Acid SCHEMBL12503056 | 0.77 | ALDH1A1 (0.58) | ALDH1A1SMN1; SMN2HPGDMAOBAOC3 | |
| SCHEMBL7637707 | 0.77 | TP53 (0.66) | ALDH1A1SMN1; SMN2HPGDL3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4391980-A | FOR INVERSION OF CONFIGURATION OF OPTICALLY ACTIVE COMPOUNDS | CIBA-GEIGY CORPORATION (US) | 1983-07-05 | — | — | US | disclosed |
| EP-0007605-B1 | A PROCESS FOR INVERTING THE CONFIGURATION IN OPTICALLY ACTIVE COMPOUNDS AND OPTICALLY ACTIVE INTERMEDIATE COMPOUNDS AND THEIR SALTS REQUIRED THEREFOR | CIBA-GEIGY AG (CH) | 1982-09-15 | — | — | EP | disclosed |
| US-4294966-A | SALT FORMATION | CIBA-GEIGY CORPORATION (US) | 1981-10-13 | — | — | US | disclosed |
| EP-0007605-A1 | A process for inverting the configuration in optically active compounds and optically active intermediate compounds and their salts required therefor | CIBA-GEIGY AG (CH) | 1980-02-06 | — | — | EP | disclosed |
| US-4161530-A | CYCLIC SUBSTITUTED AMINO ALCOHOL BETA-RECEPTOR-BLOCKING AGENT AND TRYPTOPHANE | CIBA-GEIGY CORPORATION (US) | 1979-07-17 | — | — | US | disclosed |