Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 7/20 | 0.39 |
| ▸ | MAPT | P10636 | 4/20 | 0.39 |
| ▸ | CA2 | P00918 | 2/20 | 0.39 |
| ▸ | CA12 | O43570 | 1/20 | 0.39 |
| ▸ | CA1 | P00915 | 1/20 | 0.39 |
| ▸ | CA9 | Q16790 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 9/20 | 0.38 |
| ▸ | ALOX15 | P16050 | 8/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 5/20 | 0.38 |
| ▸ | HPGD | P15428 | 4/20 | 0.38 |
| ▸ | ALOX12 | P18054 | 3/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.38 |
| ▸ | THRB | P10828 | 2/20 | 0.37 |
| ▸ | MEN1 | O00255 | 3/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.35 |
| ▸ | HTT | P42858 | 2/20 | 0.35 |
| ▸ | RECQL | P46063 | 2/20 | 0.35 |
| ▸ | USP2 | O75604 | 2/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1683994 | 0.89 | GAA (0.47) | GAAMAPTCA2CA12CA1 | |
| SCHEMBL11191085 | 0.85 | GAA (0.41) | GAAMAPTCA2CA12CA1 | |
| SCHEMBL11195200 | 0.84 | ALDH1A1 (0.48) | GAAMAPTCA2CA12CA1 | |
| SCHEMBL11197229 | 0.82 | GAA (0.39) | GAAMAPTCA2CA12CA1 | |
| SCHEMBL11190173 | 0.82 | ALDH1A1 (0.57) | GAAMAPTCA2CA12CA1 | |
| SCHEMBL11195512 | 0.82 | GAA (0.39) | GAAMAPTCA2CA12CA1 | |
| SCHEMBL11193057 | 0.82 | ALDH1A1 (0.57) | GAAMAPTCA2CA12CA1 | |
| SCHEMBL9808936 | 0.79 | MEN1 (0.40) | GAAMAPTCA2CA12CA9 | |
| SCHEMBL11194552 | 0.78 | TRPA1 (0.43) | GAAMAPTCA2CA12CA1 | |
| SCHEMBL11196257 | 0.78 | ALDH1A1 (0.61) | GAAMAPTCA2CA12CA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0083204-A2 | 2-Aminophenol derivatives and process for their preparation | ONO PHARMACEUTICAL CO., LTD. (JP) | 1983-07-06 | — | — | EP | disclosed |