Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TMEM97 | Q5BJF2 | 3/20 | 0.61 |
| ▸ | SIGMAR1 | Q99720 | 3/20 | 0.61 |
| ▸ | HRH3 | Q9Y5N1 | 5/20 | 0.60 |
| ▸ | HRH1 | P35367 | 4/20 | 0.54 |
| ▸ | DRD2 | P14416 | 2/20 | 0.54 |
| ▸ | DRD3 | P35462 | 2/20 | 0.54 |
| ▸ | DRD1 | P21728 | 1/20 | 0.54 |
| ▸ | DRD4 | P21917 | 1/20 | 0.54 |
| ▸ | DRD5 | P21918 | 1/20 | 0.54 |
| ▸ | LTA4H | P09960 | 4/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.49 |
| ▸ | LMNA | P02545 | 1/20 | 0.49 |
| ▸ | HTR1A | P08908 | 1/20 | 0.49 |
| ▸ | HTR2A | P28223 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11464549 | 0.81 | ACHE (0.56) | SIGMAR1KDM4EHTR2A | |
| Bromide SCHEMBL11193568 | 0.80 | ACHE (0.55) | SIGMAR1KDM4EHTR2A | |
| SCHEMBL5888791 | 0.78 | HRH3 (0.74) | TMEM97SIGMAR1HRH3DRD2DRD3 | |
| SCHEMBL11462980 | 0.77 | SCN1A (0.52) | HRH3HRH1DRD1 | |
| Hydrochloric Acid SCHEMBL9646177 | 0.76 | HRH3 (0.56) | TMEM97SIGMAR1HRH3HRH1DRD2 | |
| SCHEMBL5888823 | 0.76 | SIGMAR1 (1.00) | TMEM97SIGMAR1HRH3DRD4KDM4E | |
| Hydrochloric Acid SCHEMBL11198489 | 0.76 | SCN1A (0.51) | SIGMAR1HRH1 | |
| SCHEMBL5888867 | 0.74 | HRH3 (0.68) | TMEM97SIGMAR1HRH3 | |
| SCHEMBL7033807 | 0.74 | HTR1A (0.80) | TMEM97SIGMAR1HRH3HRH1DRD2 | |
| SCHEMBL11205033 | 0.74 | MEN1 (0.41) | SIGMAR1HRH1DRD3DRD1DRD4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4414219-A | ANTICONVULSANTS, TRANQUILIZERS, ANALGESTICS | AMERICAN HOECHST CORPORATION (US) | 1983-11-08 | — | — | US | disclosed |
| US-4311703-A | PYRROLIDINE AND PIPERIDINE DERIVATIVES | AMERICAN HOECHST CORPORATION (US) | 1982-01-19 | — | — | US | disclosed |
| US-4241071-A | Antidepressant (α-phenyl-2-tolyl)azacycloalkanes | AMERICAN HOECHST CORPORATION (US) | 1980-12-23 | — | — | US | disclosed |