Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PCNA | P12004 | 5/20 | 0.86 |
| ▸ | THRB | P10828 | 9/20 | 0.67 |
| ▸ | THRA | P10827 | 6/20 | 0.67 |
| ▸ | LMNA | P02545 | 4/20 | 0.67 |
| ▸ | MEN1 | O00255 | 4/20 | 0.67 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.67 |
| ▸ | PPARG | P37231 | 3/20 | 0.67 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.67 |
| ▸ | TSHR | P16473 | 1/20 | 0.67 |
| ▸ | GABRP | O00591 | 1/20 | 0.67 |
| ▸ | GABRD | O14764 | 1/20 | 0.67 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.67 |
| ▸ | F2 | P00734 | 1/20 | 0.67 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.67 |
| ▸ | GABRB1 | P18505 | 1/20 | 0.67 |
| ▸ | GABRG2 | P18507 | 1/20 | 0.67 |
| ▸ | GABRB3 | P28472 | 1/20 | 0.67 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.67 |
| ▸ | GABRA5 | P31644 | 1/20 | 0.67 |
| ▸ | GABRA3 | P34903 | 1/20 | 0.67 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL445767 | 0.92 | PCNA (1.00) | PCNATHRBTHRALMNAMEN1 | |
| SCHEMBL428139 | 0.92 | PCNA (1.00) | PCNATHRBTHRALMNAMEN1 | |
| SCHEMBL1487713 | 0.92 | PCNA (1.00) | PCNATHRBTHRALMNAMEN1 | |
| Water SCHEMBL28780882 | 0.91 | PCNA (0.97) | PCNATHRBTHRALMNAMEN1 | |
| Water SCHEMBL28780879 | 0.91 | PCNA (0.97) | PCNATHRBTHRALMNAMEN1 | |
| SCHEMBL4439595 | 0.91 | PCNA (0.97) | PCNATHRBTHRALMNAMEN1 | |
| SCHEMBL19048382 | 0.87 | PCNA (0.84) | PCNATHRBTHRALMNAMEN1 | |
| SCHEMBL5124875 | 0.85 | PCNA (0.81) | PCNATHRBTHRALMNAMEN1 | |
| Azobenzene SCHEMBL11883187 | 0.84 | PCNA (0.82) | PCNATHRBTHRALMNAMEN1 | |
| SCHEMBL31160348 | 0.84 | PCNA (0.78) | PCNATHRBTHRALMNAMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0079489-A1 | Methotrexate-labeled iodothyronine conjugates and method, reagent means and test device for the determination of iodothyronine in or iodothyronine uptake of a liquid sample | MILES LABORATORIES, INC. (US) | 1983-05-25 | — | — | EP | disclosed |