SCHEMBL445767

SCHEMBL445767

N[C@@H](Cc1cc(I)c(Oc2ccc(O)cc2)c(I)c1)C(=O)O

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
PCNA P12004 6/20 1.00
THRB P10828 9/20 0.77
THRA P10827 6/20 0.77
LMNA P02545 4/20 0.77
MEN1 O00255 4/20 0.77
KMT2A Q03164 4/20 0.77
PPARG P37231 3/20 0.77
CYP2D6 P10635 1/20 0.77
TSHR P16473 1/20 0.77
GABRP O00591 1/20 0.77
GABRD O14764 1/20 0.77
ABCB11 O95342 1/20 0.77
F2 P00734 1/20 0.77
GABRA1 P14867 1/20 0.77
GABRB1 P18505 1/20 0.77
GABRG2 P18507 1/20 0.77
GABRB3 P28472 1/20 0.77
ADORA1 P30542 1/20 0.77
GABRA5 P31644 1/20 0.77
GABRA3 P34903 1/20 0.77

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL428139 1.00 PCNA (1.00) PCNATHRBTHRALMNAMEN1
SCHEMBL1487713 1.00 PCNA (1.00) PCNATHRBTHRALMNAMEN1
Water SCHEMBL28780882 0.99 PCNA (0.97) PCNATHRBTHRALMNAMEN1
SCHEMBL4439595 0.99 PCNA (0.97) PCNATHRBTHRALMNAMEN1
Water SCHEMBL28780879 0.99 PCNA (0.97) PCNATHRBTHRALMNAMEN1
SCHEMBL11198581 0.92 PCNA (0.86) PCNATHRBTHRALMNAMEN1
SCHEMBL19048382 0.91 PCNA (0.84) PCNATHRBTHRALMNAMEN1
Azobenzene SCHEMBL11883178 0.91 PCNA (0.82) PCNATHRBTHRALMNAMEN1
Azobenzene SCHEMBL11883187 0.91 PCNA (0.82) PCNATHRBTHRALMNAMEN1
SCHEMBL5124875 0.90 PCNA (0.81) PCNATHRBTHRALMNAMEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1231 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4747627-A1 METHODS AND SYSTEMS FOR PREDICTIVE CLASSIFICATION BY MASS SPECTROMETRY AND TRAINED LARGE SPECTRAL MODELS Matterworks Inc (US) 2026-05-27 EP claimed
EP-4733383-A1 CULTURE MEDIUM AND BLOOD CELL CLONE, AND METHOD FOR PRODUCING SAME Japan Institute for Health Security (JP) 2026-04-29 EP claimed
US-20260097100-A1 CANCER TREATMENT BY INDUCTION OF TUMOR AND STEM CELL DIFFERENTIATION LATHAM KEITH ROGER (US) 2026-04-09 US claimed
EP-4688727-A1 NOVEL L-THYROXINE RADIOIODINE LABEL AND PROCESS FOR PRODUCTION THEREOF Forschungszentrum Jülich GmbH (DE) 2026-02-11 EP claimed
EP-4684002-A2 THYROCYTES AND USES THEREOF Lifenet Health (US) 2026-01-28 EP claimed
US-20250345488-A1 CROSSLINKED HYDROGELS WITH ENHANCED RADIOPACITY FOR MEDICAL APPLICATIONS BOSTON SCIENTIFIC SCIMED, INC. (US) 2025-11-13 US claimed
CN-120121693-A Identification of thyroid hormones using reactive heterogeneous nanopores 南京大学 2025-06-10 CN claimed
WO-2025019764-A1 METHODS AND SYSTEMS FOR PREDICTIVE CLASSIFICATION BY MASS SPECTROMETRY AND TRAINED LARGE SPECTRAL MODELS MATTERWORKS INC (US) 2025-01-23 WO claimed
WO-2024262610-A1 CULTURE MEDIUM AND BLOOD CELL CLONE, AND METHOD FOR PRODUCING SAME 国立研究開発法人国立国際医療研究センター 2024-12-26 WO claimed
US-20240355474-A1 METHODS FOR DETERMINING THE BENEFITS AND RISKS IN HEALTHCARE APPLICATIONS MATT JR RICHARD GEORGE (US) 2024-10-24 US claimed
EP-0467466-A1 Method for the purification of immunoreactive labeled thyroxine conjugates EASTMAN KODAK COMPANY (US) 1992-01-22 EP claimed
US-4711855-A Derivatives of 3,5,3-triiodothyronine CIBA CORNING DIAGNOSTICS CORP. (US) 1987-12-08 US claimed
EP-0073865-B1 DERIVATIVES OF IODOTHYRONINE COMPOUNDS AND THEIR USE IN AN ASSAY FOR THE FREE IODOTHYRONINE COMPOUNDS AMERSHAM INTERNATIONAL plc (GB) 1986-01-29 EP claimed
EP-0093653-B1 PROCESS FOR THE PREPARATION OF IODO-THYRONINES AND IODO-THYROACETIC ACIDS BY ELECTROCHEMICAL REDUCTION AT A CONTROLLED POTENTIAL SPIRAL Société à responsabilité limitée dite : (FR) 1985-07-10 EP claimed
US-4524223-A CHROMATOGRAPHIC SEPARATION OF DIASTEREOMERIC ESTERS UOP INC. (US) 1985-06-18 US claimed
US-4490221-A Process for preparing iodothyronines and iodothyroacetic acids by electrochemical reduction at controlled potential SPIRAL SOCIETE A RESPONSABILITE LIMITEE DITE (FR) 1984-12-25 US claimed
US-4426453-A Derivatives of iodothyronine compounds and their use in an assay for the free iodothyronine compounds AMERSHAM INTERNATIONAL LIMITED (GB) 1984-01-17 US claimed
US-4418225-A ESTERIFICATION WITH AMINO ACIDS UOP INC. (US) 1983-11-29 US claimed
EP-0093653-A1 Process for the preparation of iodo-thyronines and iodo-thyroacetic acids by electrochemical reduction at a controlled potential SPIRAL Société à responsabilité limitée dite : (FR) 1983-11-09 EP claimed
EP-0073865-A1 Derivatives of iodothyronine compounds and their use in an assay for the free iodothyronine compounds AMERSHAM INTERNATIONAL plc (GB) 1983-03-16 EP claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20260097100-A1 CANCER TREATMENT BY INDUCTION OF TUMOR AND STEM CELL DIFFERENTIATION TPO, TSHR, THRB PCNA 4188/4885THRB 3/4885THRA 4/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.