SCHEMBL428139

SCHEMBL428139

NC(Cc1cc(I)c(Oc2ccc(O)cc2)c(I)c1)C(=O)O

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
PCNA P12004 6/20 1.00
THRB P10828 9/20 0.77
THRA P10827 6/20 0.77
LMNA P02545 4/20 0.77
MEN1 O00255 4/20 0.77
KMT2A Q03164 4/20 0.77
PPARG P37231 3/20 0.77
CYP2D6 P10635 1/20 0.77
TSHR P16473 1/20 0.77
GABRP O00591 1/20 0.77
GABRD O14764 1/20 0.77
ABCB11 O95342 1/20 0.77
F2 P00734 1/20 0.77
GABRA1 P14867 1/20 0.77
GABRB1 P18505 1/20 0.77
GABRG2 P18507 1/20 0.77
GABRB3 P28472 1/20 0.77
ADORA1 P30542 1/20 0.77
GABRA5 P31644 1/20 0.77
GABRA3 P34903 1/20 0.77

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1487713 1.00 PCNA (1.00) PCNATHRBTHRALMNAMEN1
SCHEMBL445767 1.00 PCNA (1.00) PCNATHRBTHRALMNAMEN1
Water SCHEMBL28780882 0.99 PCNA (0.97) PCNATHRBTHRALMNAMEN1
SCHEMBL4439595 0.99 PCNA (0.97) PCNATHRBTHRALMNAMEN1
Water SCHEMBL28780879 0.99 PCNA (0.97) PCNATHRBTHRALMNAMEN1
SCHEMBL11198581 0.92 PCNA (0.86) PCNATHRBTHRALMNAMEN1
SCHEMBL19048382 0.91 PCNA (0.84) PCNATHRBTHRALMNAMEN1
Azobenzene SCHEMBL11883178 0.91 PCNA (0.82) PCNATHRBTHRALMNAMEN1
Azobenzene SCHEMBL11883187 0.91 PCNA (0.82) PCNATHRBTHRALMNAMEN1
SCHEMBL5124875 0.90 PCNA (0.81) PCNATHRBTHRALMNAMEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 442 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4733383-A1 CULTURE MEDIUM AND BLOOD CELL CLONE, AND METHOD FOR PRODUCING SAME Japan Institute for Health Security (JP) 2026-04-29 EP claimed
WO-2024262610-A1 CULTURE MEDIUM AND BLOOD CELL CLONE, AND METHOD FOR PRODUCING SAME 国立研究開発法人国立国際医療研究センター 2024-12-26 WO claimed
CN-114609266-B Application of marker in preparation of diagnostic reagent for thyroid related diseases 徐州医科大学 2023-03-24 CN claimed
CN-114609265-B Method for detecting eight thyroid hormone markers in serum by liquid chromatography tandem mass spectrometry technology 徐州医科大学 2023-01-24 CN claimed
US-20220265775-A1 COMPOSITIONS AND METHODS FOR TREATING PULMONARY EDEMA OR LUNG INFLAMMATION UNIV MINNESOTA (US) 2022-08-25 US claimed
CN-114609266-A Application of marker in preparation of diagnostic reagent for thyroid related diseases 徐州医科大学 2022-06-10 CN claimed
CN-114609265-A Method for detecting eight thyroid hormone markers in serum by liquid chromatography tandem mass spectrometry technology 徐州医科大学 2022-06-10 CN claimed
CN-112367979-A Electrospun fibers for local delivery of anti-inflammatory and pro-myelinating drugs 博洛尼亚大学 2021-02-12 CN claimed
WO-2021021927-A1 COMPOSITIONS AND METHODS FOR TREATING PULMONARY EDEMA OR LUNG INFLAMMATION REGENTS OF THE UNIVERSITY OF MINNESOTA (US) 2021-02-04 WO claimed
WO-2020254587-A1 THYROID HORMONE OR METABOLITE FOR USE IN THE TREATMENT OF A PERIPHERAL VESTIBULOPATHY CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (CNRS) (FR) 2020-12-24 WO claimed
WO-1999045967-A1 MANGANESE CHELATES WITH HIGH RELAXIVITY IN SERUM BRACCO S.P.A. (IT) 1999-09-16 WO claimed
WO-1999029640-A2 COMPOSITIONS AND METHODS FOR MODULATING THE ACTIVITY OF FIBROBLAST GROWTH FACTOR EISAI CO., LTD. (JP) 1999-06-17 WO claimed
EP-0920307-A2 DERIVATES FROM BISARYLTETRACARBONACID, AND PHARMARCEUTICAL PRODUCT CONTAINING THEM Roche Diagnostics GmbH (DE) 1999-06-09 EP claimed
WO-1998006386-A2 DERIVATES FROM BISARYLTETRACARBONACID, AND PHARMARCEUTICAL PRODUCT CONTAINING THEM ROCHE DIAGNOSTICS GMBH (DE) 1998-02-19 WO claimed
EP-0467466-A1 Method for the purification of immunoreactive labeled thyroxine conjugates EASTMAN KODAK COMPANY (US) 1992-01-22 EP claimed
US-4711855-A Derivatives of 3,5,3-triiodothyronine CIBA CORNING DIAGNOSTICS CORP. (US) 1987-12-08 US claimed
EP-0093653-B1 PROCESS FOR THE PREPARATION OF IODO-THYRONINES AND IODO-THYROACETIC ACIDS BY ELECTROCHEMICAL REDUCTION AT A CONTROLLED POTENTIAL SPIRAL Société à responsabilité limitée dite : (FR) 1985-07-10 EP claimed
US-4524223-A CHROMATOGRAPHIC SEPARATION OF DIASTEREOMERIC ESTERS UOP INC. (US) 1985-06-18 US claimed
US-4490221-A Process for preparing iodothyronines and iodothyroacetic acids by electrochemical reduction at controlled potential SPIRAL SOCIETE A RESPONSABILITE LIMITEE DITE (FR) 1984-12-25 US claimed
US-4418225-A ESTERIFICATION WITH AMINO ACIDS UOP INC. (US) 1983-11-29 US claimed