Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PCNA | P12004 | 6/20 | 0.97 |
| ▸ | THRB | P10828 | 9/20 | 0.75 |
| ▸ | THRA | P10827 | 6/20 | 0.75 |
| ▸ | LMNA | P02545 | 4/20 | 0.75 |
| ▸ | MEN1 | O00255 | 4/20 | 0.75 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.75 |
| ▸ | PPARG | P37231 | 3/20 | 0.75 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.75 |
| ▸ | TSHR | P16473 | 1/20 | 0.75 |
| ▸ | GABRP | O00591 | 1/20 | 0.75 |
| ▸ | GABRD | O14764 | 1/20 | 0.75 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.75 |
| ▸ | F2 | P00734 | 1/20 | 0.75 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.75 |
| ▸ | GABRB1 | P18505 | 1/20 | 0.75 |
| ▸ | GABRG2 | P18507 | 1/20 | 0.75 |
| ▸ | GABRB3 | P28472 | 1/20 | 0.75 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.75 |
| ▸ | GABRA5 | P31644 | 1/20 | 0.75 |
| ▸ | GABRA3 | P34903 | 1/20 | 0.75 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL428139 | 0.99 | PCNA (1.00) | PCNATHRBTHRALMNAMEN1 | |
| SCHEMBL445767 | 0.99 | PCNA (1.00) | PCNATHRBTHRALMNAMEN1 | |
| SCHEMBL1487713 | 0.99 | PCNA (1.00) | PCNATHRBTHRALMNAMEN1 | |
| Water SCHEMBL28780879 | 0.97 | PCNA (0.97) | PCNATHRBTHRALMNAMEN1 | |
| Water SCHEMBL28780882 | 0.97 | PCNA (0.97) | PCNATHRBTHRALMNAMEN1 | |
| SCHEMBL11198581 | 0.91 | PCNA (0.86) | PCNATHRBTHRALMNAMEN1 | |
| SCHEMBL19048382 | 0.90 | PCNA (0.84) | PCNATHRBTHRALMNAMEN1 | |
| Azobenzene SCHEMBL11883187 | 0.90 | PCNA (0.82) | PCNATHRBTHRALMNAMEN1 | |
| Azobenzene SCHEMBL11883178 | 0.90 | PCNA (0.82) | PCNATHRBTHRALMNAMEN1 | |
| SCHEMBL5124875 | 0.89 | PCNA (0.81) | PCNATHRBTHRALMNAMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20090297566-A1 | Oxygen-impervious packaging with optional oxygen scavenger, stabilized thyroid hormone compositions and methods for storing thyroid hormone pharmaceutical compositions | KING PHARMACEUTICALS, INC. | 2009-12-03 | — | — | US | disclosed |
| EP-1835897-A2 | OXYGEN-IMPERVIOUS PACKAGING WITH OPTIONAL OXYGEN SCAVENGER, STABILIZED THYROID HORMONE COMPOSITIONS AND METHODS FOR STORING THYROID HORMONE PHARMACEUTICAL COMPOSITIONS | King Pharmaceuticals Research and Development Inc. (US) | 2007-09-26 | — | — | EP | disclosed |
| US-20060183804-A1 | Oxygen-impervious packaging with optional oxygen scavenger, stabilized thyroid hormone compositions and methods for storing thyroid hormone pharmaceutical compositions | CREDIT SUISSE AG | 2006-08-17 | — | — | US | disclosed |
| WO-2006071844-A2 | OXYGEN-IMPERVIOUS PACKAGING AND METHODS FOR STORING THYROID HORMONE | KING PHARMACEUTICALS RESEARCH AND DEVELOPMENT, INC. (US) | 2006-07-06 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060183804-A1 | Oxygen-impervious packaging with optional oxygen scavenger, stabilized thyroid hormone compositions and methods for storing thyroid hormone pharmaceutical compositions | TPO, TSHR, TRHDE | PCNA 4834/4885THRB 7/4885THRA 4/4885 |
| US-20090297566-A1 | Oxygen-impervious packaging with optional oxygen scavenger, stabilized thyroid hormone compositions and methods for storing thyroid hormone pharmaceutical compositions | TPO, TSHR, THRA | PCNA 4856/4885THRB 8/4885THRA 3/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.