Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DOT1L | Q8TEK3 | 1/20 | 0.54 |
| ▸ | AHCY | P23526 | 6/20 | 0.53 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.53 |
| ▸ | TMEM97 | Q5BJF2 | 1/20 | 0.53 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.53 |
| ▸ | HSP90B1 | P14625 | 4/20 | 0.50 |
| ▸ | ADORA3 | P0DMS8 | 4/20 | 0.50 |
| ▸ | TSHR | P16473 | 3/20 | 0.50 |
| ▸ | HSP90AA1 | P07900 | 3/20 | 0.50 |
| ▸ | ADORA2B | P29275 | 3/20 | 0.50 |
| ▸ | ADORA1 | P30542 | 3/20 | 0.50 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.50 |
| ▸ | ADORA2A | P29274 | 2/20 | 0.50 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.50 |
| ▸ | TMIGD3 | P0DMS9 | 1/20 | 0.50 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.50 |
| ▸ | MEN1 | O00255 | 1/20 | 0.50 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10885019 | 1.00 | DOT1L (0.54) | DOT1LAHCYHIF1ATMEM97SIGMAR1 | |
| SCHEMBL10885160 | 0.88 | ADORA2A (0.46) | ADORA2BADORA2A | |
| SCHEMBL10886173 | 0.86 | AHCY (0.64) | AHCYHIF1ATMEM97SIGMAR1HSP90B1 | |
| SCHEMBL10886606 | 0.83 | AHCY (0.65) | AHCYHIF1ATMEM97SIGMAR1HSP90B1 | |
| SCHEMBL10884776 | 0.74 | AHCY (0.51) | DOT1LAHCYHIF1ATMEM97SIGMAR1 | |
| SCHEMBL10884690 | 0.74 | TRDMT1 (0.49) | DOT1LAHCYHIF1AADORA2BADORA2A | |
| SCHEMBL10885013 | 0.73 | AHCY (0.51) | AHCYHIF1ATMEM97SIGMAR1HSP90B1 | |
| SCHEMBL10887916 | 0.73 | AHCY (0.54) | DOT1LAHCYHIF1AHSP90B1 | |
| SCHEMBL10884608 | 0.73 | TRDMT1 (0.51) | DOT1LAHCYHIF1ATMEM97SIGMAR1 | |
| SCHEMBL10886849 | 0.73 | TRDMT1 (0.51) | DOT1LAHCYHIF1ATMEM97SIGMAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0071926-A1 | New ribofuranuronic acid derivatives, processes for preparation thereof and pharmaceutical compositions thereof | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1983-02-16 | — | — | EP | disclosed |