Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SPHK1 | Q9NYA1 | 12/20 | 0.50 |
| ▸ | S1PR1 | P21453 | 5/20 | 0.50 |
| ▸ | S1PR2 | O95136 | 3/20 | 0.50 |
| ▸ | S1PR3 | Q99500 | 4/20 | 0.49 |
| ▸ | SPHK2 | Q9NRA0 | 1/20 | 0.48 |
| ▸ | S1PR4 | O95977 | 3/20 | 0.46 |
| ▸ | S1PR5 | Q9H228 | 2/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL112512 | 0.87 | NAAA (0.50) | ALDH1A1 | |
| SCHEMBL112307 | 0.87 | NAAA (0.50) | ALDH1A1 | |
| SCHEMBL5366842 | 0.87 | NAAA (0.50) | ALDH1A1 | |
| SCHEMBL8029779 | 0.87 | NAAA (0.50) | ALDH1A1 | |
| SCHEMBL110651 | 0.87 | NAAA (0.50) | ALDH1A1 | |
| SCHEMBL114444 | 0.87 | NAAA (0.50) | ALDH1A1 | |
| SCHEMBL5220076 | 0.87 | NAAA (0.50) | ALDH1A1 | |
| SCHEMBL110652 | 0.87 | NAAA (0.50) | ALDH1A1 | |
| SCHEMBL109917 | 0.87 | NAAA (0.50) | ALDH1A1 | |
| SCHEMBL114445 | 0.87 | NAAA (0.50) | ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0068739-A1 | Sulphur-containing 5-hydroxy-alkanoic acid derivatives, their use as pharmaceutical preparations and process for their production | Lilly Industries Limited (GB) | 1983-01-05 | — | — | EP | disclosed |