Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR2A | P28223 | 1/20 | 0.54 |
| ▸ | HTT | P42858 | 2/20 | 0.48 |
| ▸ | RAB9A | P51151 | 1/20 | 0.48 |
| ▸ | IDO1 | P14902 | 2/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.47 |
| ▸ | MAOB | P27338 | 1/20 | 0.47 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.47 |
| ▸ | MAPT | P10636 | 1/20 | 0.45 |
| ▸ | POLB | P06746 | 1/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.45 |
| ▸ | GAA | P10253 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11204684 | 0.89 | HTR2A (0.52) | HTR2AHTTRAB9AIDO1L3MBTL1 | |
| SCHEMBL8530085 | 0.85 | HTR2A (0.56) | HTR2AHTTRAB9AIDO1L3MBTL1 | |
| SCHEMBL37664 | 0.83 | HTR2A (0.62) | HTR2AHTTRAB9AIDO1ALDH1A1 | |
| SCHEMBL27669847 | 0.82 | HTR2A (0.53) | HTR2AHTTRAB9AIDO1ALDH1A1 | |
| SCHEMBL6141153 | 0.82 | HTR2A (0.59) | HTR2AHTTRAB9AIDO1L3MBTL1 | |
| SCHEMBL6141208 | 0.80 | HTR2A (0.64) | HTR2AHTTRAB9AIDO1L3MBTL1 | |
| SCHEMBL1029307 | 0.80 | HTR2A (0.59) | HTR2AHTTRAB9AIDO1ALDH1A1 | |
| SCHEMBL4725847 | 0.80 | HTR2A (0.59) | HTR2AHTTRAB9AIDO1ALDH1A1 | |
| SCHEMBL11390522 | 0.79 | IDO1 (0.50) | HTR2AHTTRAB9AIDO1L3MBTL1 | |
| SCHEMBL11199226 | 0.79 | HTR2A (0.56) | HTR2AHTTRAB9AIDO1L3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4395418-A | 6-HYDROXYETHYL SUBSTITUTED ANTIBIOTICS | SANKYO COMPANY LIMITED (JP) | 1983-07-26 | — | — | US | disclosed |