Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR2A | P28223 | 1/20 | 0.56 |
| ▸ | HTT | P42858 | 2/20 | 0.50 |
| ▸ | IDO1 | P14902 | 2/20 | 0.50 |
| ▸ | RAB9A | P51151 | 1/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.49 |
| ▸ | MAOB | P27338 | 1/20 | 0.49 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.49 |
| ▸ | MAPT | P10636 | 1/20 | 0.47 |
| ▸ | POLB | P06746 | 1/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.46 |
| ▸ | GAA | P10253 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL37664 | 0.85 | HTR2A (0.62) | HTR2AHTTIDO1RAB9AALDH1A1 | |
| SCHEMBL11199220 | 0.85 | HTR2A (0.54) | HTR2AHTTIDO1RAB9AALDH1A1 | |
| SCHEMBL27669847 | 0.85 | HTR2A (0.53) | HTR2AHTTIDO1RAB9AALDH1A1 | |
| SCHEMBL11204684 | 0.83 | HTR2A (0.52) | HTR2AHTTIDO1RAB9AALDH1A1 | |
| SCHEMBL6141208 | 0.83 | HTR2A (0.64) | HTR2AHTTIDO1RAB9AALDH1A1 | |
| SCHEMBL1029307 | 0.82 | HTR2A (0.59) | HTR2AHTTIDO1RAB9AALDH1A1 | |
| SCHEMBL4725847 | 0.82 | HTR2A (0.59) | HTR2AHTTIDO1RAB9AALDH1A1 | |
| SCHEMBL9669560 | 0.81 | IDO1 (0.53) | HTR2AHTTIDO1RAB9AALDH1A1 | |
| SCHEMBL6141153 | 0.81 | HTR2A (0.59) | HTR2AHTTIDO1RAB9AALDH1A1 | |
| SCHEMBL10801165 | 0.80 | HTR2A (0.58) | HTR2AHTTIDO1RAB9AALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 32 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4639441-A | ANTIBACTERIAL PENICILLINS | SANKYO COMPANY LIMITED (JP) | 1987-01-27 | — | — | US | claimed |
| US-4383945-A | 4-Substituted-2-oxoazetidine compounds and processes for the preparation thereof | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1983-05-17 | — | — | US | claimed |
| EP-0073451-A2 | Carbapenam compound and processes for the preparation thereof | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1983-03-09 | — | — | EP | claimed |
| US-4348264-A | Photocatalyzed process for producing carbapenams and carbapen-2-ems | PFIZER INC. (US) | 1982-09-07 | — | — | US | claimed |
| EP-0504612-B1 | Novel 4-substituted azetidinones as precursors to 2-substituted-3-carboxy carbapenem antibiotics and a method of producing them | AMERICAN CYANAMID CO (US) | 1998-01-21 | — | — | EP | disclosed |
| US-5700930-A | 4-substituted azetidinones as precursors to 2-substituted-3-carboxy carbapenem antibiotics and a method of producing them | AMERICAN CYANAMID COMPANY (US) | 1997-12-23 | — | — | US | disclosed |
| US-5656753-A | 4-substituted azetidinones as precursors to 2-substituted-3-carboxy carbapenem antibiotics and a method of producing them | AMERICAN CYANAMID COMPANY (US) | 1997-08-12 | — | — | US | disclosed |
| EP-0126587-B1 | Carboxylic thio-pyrrolidinyl beta-lactam compounds and production thereof | SUMITOMO PHARMA (JP) | 1995-04-19 | — | — | EP | disclosed |
| US-5371215-A | 4-substituted azetidinones as precursors to 2-substituted-3-carboxy carbapenem antibiotics and a method of producing them | AMERICAN CYANAMID COMPANY (US) | 1994-12-06 | — | — | US | disclosed |
| EP-0280771-B1 | 3-Pyrrolidinylthio-1-azabicyclo[3.2.0]hept-2-ene-2-carboxylic acid derivatives and processes for the preparation thereof | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1993-07-28 | — | — | EP | disclosed |
| US-5189158-A | 4-SUBSTITUTED AZETIDINONES AS PRECURSORS TO 2-SUBSTITUTED-3-CARBOXY CARBAPENEM ANTIBIOTICS AND A METHOD OF PRODUCING THEM | AMERICAN CYANAMID COMPANY (US) | 1993-02-23 | — | — | US | disclosed |
| EP-0504612-A2 | Novel 4-substituted azetidinones as precursors to 2-substituted-3-carboxy carbapenem antibiotics and a method of producing them | AMERICAN CYANAMID COMPANY (US) | 1992-09-23 | — | — | EP | disclosed |
| US-4482565-A | β-Lactam-containing antibacterial agents and β-lactamase inhibitors | FARMITALIA CARLO ERBA S.P.A. (IT) | 1984-11-13 | — | — | US | disclosed |
| EP-0033209-B1 | BETA-LACTAM CONTAINING COMPOUNDS, THEIR PREPARATION AND USE | BEECHAM GROUP PLC (GB) | 1984-06-13 | — | — | EP | disclosed |
| US-4446146-A | β-Lactam containing compounds, their preparation and use | BEECHAM GROUP LIMITED (GB) | 1984-05-01 | — | — | US | disclosed |
| US-4428961-A | THIENAMYCIN ANTIBIOTICS | BEECHAM GROUP LIMITED (GB) | 1984-01-31 | — | — | US | disclosed |
| EP-0089139-A2 | Antibiotics, their preparation and use | BEECHAM GROUP PLC (GB) | 1983-09-21 | — | — | EP | disclosed |
| US-4395418-A | 6-HYDROXYETHYL SUBSTITUTED ANTIBIOTICS | SANKYO COMPANY LIMITED (JP) | 1983-07-26 | — | — | US | disclosed |
| EP-0070204-A2 | Carboxylic beta-lactam compounds and the preparation thereof | SUMITOMO PHARMACEUTICALS COMPANY, LIMITED (JP) | 1983-01-19 | — | — | EP | disclosed |
| EP-0033209-A1 | Beta-lactam containing compounds, their preparation and use | BEECHAM GROUP PLC (GB) | 1981-08-05 | — | — | EP | disclosed |