Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.33 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.31 |
| ▸ | HTT | P42858 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13064875 | 0.94 | ALDH1A1 (0.36) | ALDH1A1CHRNB2CHRNA4KDM4EL3MBTL1 | |
| SCHEMBL863190 | 0.79 | INMT (0.30) | — | |
| SCHEMBL1110106 | 0.74 | — | — | |
| SCHEMBL28293255 | 0.71 | LMNA (0.30) | — | |
| SCHEMBL7825892 | 0.67 | — | — | |
| SCHEMBL12182626 | 0.66 | — | — | |
| SCHEMBL7831654 | 0.63 | — | — | |
| SCHEMBL7837916 | 0.63 | INMT (0.33) | — | |
| SCHEMBL20156968 | 0.63 | — | — | |
| SCHEMBL30431874 | 0.63 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8153793-B2 | Sulfonamide derivative having PGD2 receptor antagonistic activity | SHIONOGI & CO., LTD. (JP) | 2012-04-10 | — | — | US | disclosed |