Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.53 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.53 |
| ▸ | ATM | Q13315 | 1/20 | 0.53 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.51 |
| ▸ | RAB9A | P51151 | 5/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.50 |
| ▸ | NPC1 | O15118 | 3/20 | 0.50 |
| ▸ | LMNA | P02545 | 1/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.49 |
| ▸ | MEN1 | O00255 | 3/20 | 0.49 |
| ▸ | ELANE | P08246 | 2/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.47 |
| ▸ | MAPT | P10636 | 2/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.46 |
| ▸ | THRB | P10828 | 1/20 | 0.46 |
| ▸ | GFER | P55789 | 1/20 | 0.46 |
| ▸ | PKM | P14618 | 1/20 | 0.46 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.44 |
| ▸ | GAA | P10253 | 1/20 | 0.44 |
| ▸ | HPGD | P15428 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9481531 | 0.91 | ELANE (0.59) | L3MBTL1TDP1ATMNPSR1RAB9A | |
| SCHEMBL11841636 | 0.82 | MAPT (0.56) | TDP1RAB9ASMN1; SMN2NPC1LMNA | |
| SCHEMBL13366566 | 0.81 | ELANE (0.62) | L3MBTL1TDP1ATMNPSR1RAB9A | |
| Hydrochloric Acid SCHEMBL11841634 | 0.80 | MAPT (0.54) | TDP1RAB9ASMN1; SMN2NPC1LMNA | |
| SCHEMBL13969403 | 0.79 | RAB9A (0.41) | L3MBTL1TDP1ATMNPSR1RAB9A | |
| SCHEMBL9806081 | 0.79 | ACHE (0.61) | L3MBTL1NPSR1RAB9ASMN1; SMN2NPC1 | |
| Hydrochloric Acid SCHEMBL10701922 | 0.78 | TDP1 (0.48) | L3MBTL1TDP1ATMRAB9ASMN1; SMN2 | |
| SCHEMBL2742818 | 0.78 | HPGD (0.70) | L3MBTL1TDP1ATMNPSR1RAB9A | |
| SCHEMBL9481027 | 0.78 | MTNR1A (0.56) | L3MBTL1TDP1ATMLMNAKMT2A | |
| SCHEMBL14063384 | 0.77 | ELANE (0.61) | L3MBTL1TDP1ATMNPSR1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0072905-A1 | Bis-oxadiazolyl-naphthalenes, process for their preparation and their application | HOECHST AKTIENGESELLSCHAFT (DE) | 1983-03-02 | — | — | EP | disclosed |