Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPR84 | Q9NQS5 | 10/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.35 |
| ▸ | HIF1A | Q16665 | 6/20 | 0.34 |
| ▸ | EPAS1 | Q99814 | 6/20 | 0.34 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | USP2 | O75604 | 1/20 | 0.33 |
| ▸ | PABPC1 | P11940 | 1/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16516482 | 0.69 | GPR84 (0.39) | GPR84HIF1AEPAS1TSHR | |
| SCHEMBL4170441 | 0.69 | GPR84 (0.39) | GPR84HIF1AEPAS1TSHR | |
| SCHEMBL3662908 | 0.69 | — | — | |
| SCHEMBL7036571 | 0.69 | — | — | |
| SCHEMBL1489327 | 0.63 | HIF1A (0.75) | HIF1ATSHRTDP1 | |
| SCHEMBL14616447 | 0.63 | HIF1A (0.75) | HIF1ATSHRTDP1 | |
| SCHEMBL495540 | 0.63 | HIF1A (0.75) | HIF1ATSHRTDP1 | |
| SCHEMBL1676795 | 0.63 | HIF1A (0.75) | HIF1ATSHRTDP1 | |
| SCHEMBL17369100 | 0.63 | HIF1A (0.75) | HIF1ATSHRTDP1 | |
| SCHEMBL2153965 | 0.63 | HIF1A (0.75) | HIF1ATSHRTDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0079049-A2 | Novel substituted alkanoylimidazol-2-one derivatives | MERRELL DOW PHARMACEUTICALS INC. (US) | 1983-05-18 | — | — | EP | disclosed |