SCHEMBL1676795

SCHEMBL1676795

O=CCCCCCCCCCCCCCCCCCCC=O

nearest known ligand 0.75

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
HIF1A Q16665 1/20 0.75
TSHR P16473 2/20 0.69
FAAH O00519 2/20 0.58
TRPV1 Q8NER1 2/20 0.58
ALDH1A1 P00352 2/20 0.44
TDP1 Q9NUW8 2/20 0.37
MAPK1 P28482 1/20 0.33
MAPT P10636 1/20 0.32
EPHX1 P07099 1/20 0.32
ADH1B P00325 1/20 0.32
ADH1C P00326 1/20 0.32
ADH1A P07327 1/20 0.32
ADH4 P08319 1/20 0.32
ADH7 P40394 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2153681 1.00 HIF1A (0.75) HIF1ATSHRFAAHTRPV1ALDH1A1
SCHEMBL14337652 1.00 HIF1A (0.75) HIF1ATSHRFAAHTRPV1ALDH1A1
SCHEMBL495540 1.00 HIF1A (0.75) HIF1ATSHRFAAHTRPV1ALDH1A1
SCHEMBL3227000 1.00 HIF1A (0.75) HIF1ATSHRFAAHTRPV1ALDH1A1
SCHEMBL1676895 1.00 HIF1A (0.75) HIF1ATSHRFAAHTRPV1ALDH1A1
SCHEMBL17369100 1.00 HIF1A (0.75) HIF1ATSHRFAAHTRPV1ALDH1A1
SCHEMBL1489327 1.00 HIF1A (0.75) HIF1ATSHRFAAHTRPV1ALDH1A1
SCHEMBL14616447 1.00 HIF1A (0.75) HIF1ATSHRFAAHTRPV1ALDH1A1
SCHEMBL2153965 1.00 HIF1A (0.75) HIF1ATSHRFAAHTRPV1ALDH1A1
SCHEMBL2155121 1.00 HIF1A (0.75) HIF1ATSHRFAAHTRPV1ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 76 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-119368144-A ZIF-67 nanostructure-containing high-performance photocatalysis synergistic adsorption material and preparation method and application thereof 陕西科技大学 2025-01-28 CN claimed
CN-118307789-A Resin microsphere for blood perfusion and preparation method and application thereof 河南驼人医疗器械研究院有限公司 2024-07-09 CN claimed
CN-118047880-A Fusion protein based on shiga toxin, cross-linked pentameric protein scaffold, and preparation and application thereof 江南大学 2024-05-17 CN claimed
CN-117963883-A Biological-asphalt-based composite hard carbon composite material and preparation method thereof 丰镇市宏升炭素有限公司 2024-05-03 CN claimed
US-20190112348-A1 PROTEASE STABILIZED, ACYLATED INSULIN ANALOGUES NOVO NORDISK AS (DK) 2019-04-18 US claimed
US-10259856-B2 Protease stabilized acylated insulin analogues NOVO NORDISK A/S (DK) 2019-04-16 US claimed
US-9688737-B2 Protease stabilized acylated insulin analogues NOVO NORDISK A/S (DK) 2017-06-27 US claimed
EP-2254906-B1 PROTEASE STABILIZED, ACYLATED INSULIN ANALOGUES NOVO NORDISK AS (DK) 2016-10-05 EP claimed
EP-2910571-A1 Protease stabilized, acylated insulin analogues Novo Nordisk A/S (DK) 2015-08-26 EP claimed
US-20150210748-A1 PROTEASE STABILIZED ACYLATED INSULIN ANALOGUES NOVO NORDISK AS (DK) 2015-07-30 US claimed
US-20150210747-A1 PROTEASE STABILIZED ACYLATED INSULIN ANALOGUES NOVO NORDISK AS (DK) 2015-07-30 US claimed
US-20110105720-A1 PROTEASE STABILIZED, ACYLATED INSULIN ANALOGUES NOVO NORDISK A/S (DK) 2011-05-05 US claimed
EP-2254906-A1 PROTEASE STABILIZED, ACYLATED INSULIN ANALOGUES Novo Nordisk A/S (DK) 2010-12-01 EP claimed
WO-2009115469-A1 PROTEASE STABILIZED, ACYLATED INSULIN ANALOGUES NOVO NORDISK A/S (DK) 2009-09-24 WO claimed
CN-1206202-C Method for mfg. dien KURARAY CO (JP) 2005-06-15 CN claimed
CN-1446793-A Method for mfg. dien KURARAY CO (JP) 2003-10-08 CN claimed
CN-119368144-A ZIF-67 nanostructure-containing high-performance photocatalysis synergistic adsorption material and preparation method and application thereof 陕西科技大学 2025-01-28 CN disclosed
CN-118307789-A Resin microsphere for blood perfusion and preparation method and application thereof 河南驼人医疗器械研究院有限公司 2024-07-09 CN disclosed
EP-0374269-A1 Amine thiocyanates as accelerators for cure of polyepoxide-polyimine materials Ashland Oil, Inc. (US) 1990-06-27 EP disclosed
US-4775735-A SHELF STABILITY, QUICK-SETTING ASHLAND OIL, INC. (US) 1988-10-04 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20150210747-A1 PROTEASE STABILIZED ACYLATED INSULIN ANALOGUES IAPP, IDE, LIPE HIF1A 2353/4885TSHR 807/4885FAAH 224/4885
US-20110105720-A1 PROTEASE STABILIZED, ACYLATED INSULIN ANALOGUES IAPP, IDE, LIPE HIF1A 1903/4885TSHR 819/4885FAAH 179/4885
US-20150210748-A1 PROTEASE STABILIZED ACYLATED INSULIN ANALOGUES IAPP, IDE, LIPE HIF1A 2353/4885TSHR 807/4885FAAH 224/4885
US-20190112348-A1 PROTEASE STABILIZED, ACYLATED INSULIN ANALOGUES IAPP, IDE, LIPE HIF1A 1903/4885TSHR 819/4885FAAH 179/4885
US-10259856-B2 Protease stabilized acylated insulin analogues IAPP, IDE, LIPE HIF1A 2353/4885TSHR 807/4885FAAH 224/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.