Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.39 |
| ▸ | GAA | P10253 | 2/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.37 |
| ▸ | NPC1 | O15118 | 2/20 | 0.37 |
| ▸ | RAB9A | P51151 | 2/20 | 0.37 |
| ▸ | HPGD | P15428 | 1/20 | 0.37 |
| ▸ | TSHR | P16473 | 1/20 | 0.37 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.37 |
| ▸ | CASP3 | P42574 | 1/20 | 0.37 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.37 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.37 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 2/20 | 0.35 |
| ▸ | PARP10 | Q53GL7 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.35 |
| ▸ | SYK | P43405 | 3/20 | 0.34 |
| ▸ | PPARG | P37231 | 1/20 | 0.34 |
| ▸ | CA12 | O43570 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11199642 | 1.00 | SMN1; SMN2 (0.39) | SMN1; SMN2GAAMEN1KMT2AALDH1A1 | |
| SCHEMBL11198229 | 0.80 | ALDH1A1 (0.42) | SMN1; SMN2GAAMEN1KMT2AALDH1A1 | |
| SCHEMBL11198225 | 0.80 | ALDH1A1 (0.42) | SMN1; SMN2GAAMEN1KMT2AALDH1A1 | |
| SCHEMBL11201404 | 0.77 | SYK (0.40) | SMN1; SMN2ALDH1A1NPC1RAB9AHPGD | |
| Hydrochloric Acid SCHEMBL11201894 | 0.76 | SYK (0.39) | SMN1; SMN2GAAALDH1A1NPC1RAB9A | |
| SCHEMBL11195451 | 0.72 | P2RX7 (0.36) | SMN1; SMN2ALDH1A1NPC1RAB9AMAPK1 | |
| SCHEMBL11195449 | 0.72 | P2RX7 (0.36) | SMN1; SMN2ALDH1A1NPC1RAB9AMAPK1 | |
| SCHEMBL10263927 | 0.70 | KDM4E (0.45) | SMN1; SMN2ALDH1A1NPC1RAB9AHPGD | |
| SCHEMBL3432856 | 0.70 | SYK (0.46) | SMN1; SMN2ALDH1A1NPC1RAB9ALMNA | |
| SCHEMBL11196636 | 0.70 | SMN1; SMN2 (0.41) | SMN1; SMN2ALDH1A1NPC1RAB9ALMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4379158-A | Antisecretory imidazole amidine compounds, composition and method of use | YAMANOUCHI PHARMACEUTICAL CO., LTD. (JP) | 1983-04-05 | — | — | US | disclosed |
| US-4252819-A | ANTISECRETORY AGENTS; GASTRIC JUICE | YAMANOUCHI PHARMACEUTICAL CO., LTD. (JP) | 1981-02-24 | — | — | US | disclosed |