Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SYK | P43405 | 3/20 | 0.40 |
| ▸ | AURKB | Q96GD4 | 2/20 | 0.40 |
| ▸ | INCENP | Q9NQS7 | 2/20 | 0.40 |
| ▸ | NPC1 | O15118 | 3/20 | 0.40 |
| ▸ | RAB9A | P51151 | 3/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.40 |
| ▸ | LMNA | P02545 | 3/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
| ▸ | CASP3 | P42574 | 1/20 | 0.39 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.39 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.39 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.39 |
| ▸ | CA12 | O43570 | 1/20 | 0.38 |
| ▸ | CA1 | P00915 | 1/20 | 0.38 |
| ▸ | CA2 | P00918 | 1/20 | 0.38 |
| ▸ | CA9 | Q16790 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL11201894 | 0.99 | SYK (0.39) | SYKAURKBINCENPNPC1RAB9A | |
| Hydrochloric Acid SCHEMBL9314574 | 0.77 | LMNA (0.45) | LMNAALDH1A1KDM4ECA12CA1 | |
| SCHEMBL11199642 | 0.77 | SMN1; SMN2 (0.39) | SYKAURKBINCENPNPC1RAB9A | |
| SCHEMBL11199643 | 0.77 | SMN1; SMN2 (0.39) | SYKAURKBINCENPNPC1RAB9A | |
| SCHEMBL10263927 | 0.76 | KDM4E (0.45) | SYKAURKBINCENPNPC1RAB9A | |
| SCHEMBL11197179 | 0.76 | ALDH1A1 (0.48) | NPC1RAB9ASMN1; SMN2LMNAALDH1A1 | |
| SCHEMBL3432856 | 0.76 | SYK (0.46) | SYKAURKBINCENPNPC1RAB9A | |
| Hydrochloric Acid SCHEMBL11193716 | 0.75 | LMNA (0.48) | NPC1RAB9ASMN1; SMN2LMNAALDH1A1 | |
| Hydrochloric Acid SCHEMBL17654896 | 0.74 | ALDH1A1 (0.47) | SYKAURKBINCENPNPC1RAB9A | |
| SCHEMBL11229653 | 0.74 | ALDH1A1 (0.46) | NPC1RAB9ASMN1; SMN2LMNAALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4379158-A | Antisecretory imidazole amidine compounds, composition and method of use | YAMANOUCHI PHARMACEUTICAL CO., LTD. (JP) | 1983-04-05 | — | — | US | disclosed |
| US-4252819-A | ANTISECRETORY AGENTS; GASTRIC JUICE | YAMANOUCHI PHARMACEUTICAL CO., LTD. (JP) | 1981-02-24 | — | — | US | disclosed |