Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SYK | P43405 | 2/20 | 0.36 |
| ▸ | SMPD3 | Q9NY59 | 1/20 | 0.36 |
| ▸ | JAK2 | O60674 | 1/20 | 0.34 |
| ▸ | JAK3 | P52333 | 1/20 | 0.34 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.33 |
| ▸ | PDE4A | P27815 | 1/20 | 0.33 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.33 |
| ▸ | PDE4C | Q08493 | 1/20 | 0.33 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 3/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.32 |
| ▸ | GAA | P10253 | 2/20 | 0.32 |
| ▸ | ADORA3 | P0DMS8 | 2/20 | 0.32 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.32 |
| ▸ | USP2 | O75604 | 1/20 | 0.32 |
| ▸ | HTT | P42858 | 1/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.32 |
| ▸ | GLA | P06280 | 1/20 | 0.32 |
| ▸ | TSHR | P16473 | 1/20 | 0.32 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10963152 | 1.00 | SYK (0.36) | SYKSMPD3JAK2JAK3CHRM3 | |
| SCHEMBL10917458 | 0.98 | SMPD3 (0.36) | SYKSMPD3JAK2JAK3CHRM3 | |
| SCHEMBL10919711 | 0.87 | HTT (0.42) | JAK2JAK3HPGDALDH1A1GAA | |
| SCHEMBL11111106 | 0.86 | HTR3E (0.41) | — | |
| SCHEMBL10918062 | 0.84 | KMT2A (0.39) | SYKHPGDALDH1A1HTTKDM4E | |
| SCHEMBL10965000 | 0.75 | ALDH1A1 (0.40) | CHRM3PDE4APDE4BPDE4CPDE4D | |
| SCHEMBL10967664 | 0.75 | ALDH1A1 (0.40) | CHRM3PDE4APDE4BPDE4CPDE4D | |
| SCHEMBL8553896 | 0.73 | HPGD (0.31) | HPGD | |
| SCHEMBL10963072 | 0.73 | ALDH1A1 (0.41) | HPGDALDH1A1GAANPSR1USP2 | |
| SCHEMBL10916033 | 0.73 | SMPD3 (0.35) | SMPD3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4391807-A | 6-Substituted tetrahydroimidazo[2,1-a]phthalazines and use as bronchodilators | THE DOW CHEMICAL COMPANY (US) | 1983-07-05 | — | — | US | disclosed |