Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.37 |
| ▸ | MAPT | P10636 | 2/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.37 |
| ▸ | HTR3A | P46098 | 1/20 | 0.35 |
| ▸ | HRH4 | Q9H3N8 | 1/20 | 0.35 |
| ▸ | HCRTR1 | O43613 | 2/20 | 0.35 |
| ▸ | HCRTR2 | O43614 | 2/20 | 0.35 |
| ▸ | GGPS1 | O95749 | 1/20 | 0.34 |
| ▸ | EHMT2 | Q96KQ7 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.32 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.32 |
| ▸ | CTNNB1 | P35222 | 1/20 | 0.32 |
| ▸ | TCF7L2 | Q9NQB0 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11198545 | 0.87 | HRH4 (0.42) | KDM4EMAPTALDH1A1MAPK1L3MBTL1 | |
| SCHEMBL11200451 | 0.84 | LMNA (0.38) | KDM4EMAPTALDH1A1MAPK1L3MBTL1 | |
| SCHEMBL11205725 | 0.82 | PRKCI (0.46) | KDM4EALDH1A1 | |
| SCHEMBL11217766 | 0.81 | HCRTR1 (0.37) | KDM4EMAPTALDH1A1MAPK1L3MBTL1 | |
| SCHEMBL11204009 | 0.81 | KDM4E (0.39) | KDM4EMAPTALDH1A1MAPK1L3MBTL1 | |
| SCHEMBL11197619 | 0.81 | KDM4E (0.35) | KDM4EMAPTALDH1A1MAPK1L3MBTL1 | |
| SCHEMBL11197939 | 0.80 | HCRTR1 (0.49) | KDM4EMAPTALDH1A1MAPK1L3MBTL1 | |
| SCHEMBL11202884 | 0.79 | HCRTR1 (0.47) | KDM4EMAPTALDH1A1MAPK1L3MBTL1 | |
| SCHEMBL11207434 | 0.78 | KDM4E (0.38) | KDM4EMAPTALDH1A1MAPK1L3MBTL1 | |
| SCHEMBL11201461 | 0.78 | KDM4E (0.39) | KDM4EMAPTALDH1A1MAPK1L3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0082023-A2 | Thienopyrimidine derivatives, their preparation and their medical use | SANKYO COMPANY LIMITED (JP) | 1983-06-22 | — | — | EP | disclosed |