Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.37 |
| ▸ | ESR1 | P03372 | 1/20 | 0.35 |
| ▸ | CTNNB1 | P35222 | 1/20 | 0.35 |
| ▸ | TCF7L2 | Q9NQB0 | 1/20 | 0.35 |
| ▸ | HCRTR1 | O43613 | 2/20 | 0.35 |
| ▸ | HCRTR2 | O43614 | 2/20 | 0.35 |
| ▸ | ELANE | P08246 | 1/20 | 0.32 |
| ▸ | RAB9A | P51151 | 2/20 | 0.32 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.32 |
| ▸ | NOD2 | Q9HC29 | 1/20 | 0.32 |
| ▸ | GGPS1 | O95749 | 1/20 | 0.32 |
| ▸ | PLA2G1B | P04054 | 1/20 | 0.31 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.31 |
| ▸ | ATG4B | Q9Y4P1 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11197619 | 0.91 | KDM4E (0.35) | LMNASMN1; SMN2ALDH1A1KDM4EMAPT | |
| SCHEMBL11201197 | 0.89 | LMNA (0.38) | LMNASMN1; SMN2ALDH1A1KDM4EMAPT | |
| SCHEMBL11204009 | 0.88 | KDM4E (0.39) | LMNASMN1; SMN2ALDH1A1KDM4EMAPT | |
| SCHEMBL11217766 | 0.88 | HCRTR1 (0.37) | SMN1; SMN2ALDH1A1KDM4EMAPTMAPK1 | |
| SCHEMBL11198545 | 0.87 | HRH4 (0.42) | LMNAALDH1A1KDM4EMAPTMAPK1 | |
| SCHEMBL11207434 | 0.87 | KDM4E (0.38) | SMN1; SMN2ALDH1A1KDM4EMAPTMAPK1 | |
| SCHEMBL11200259 | 0.84 | KDM4E (0.37) | ALDH1A1KDM4EMAPTMAPK1L3MBTL1 | |
| SCHEMBL11198016 | 0.82 | PRKCI (0.43) | LMNASMN1; SMN2ESR1 | |
| Hydrochloric Acid SCHEMBL11204595 | 0.81 | PRKCI (0.43) | LMNASMN1; SMN2ESR1 | |
| SCHEMBL11201436 | 0.81 | MAPT (0.45) | LMNASMN1; SMN2ALDH1A1KDM4EMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0082023-A2 | Thienopyrimidine derivatives, their preparation and their medical use | SANKYO COMPANY LIMITED (JP) | 1983-06-22 | — | — | EP | disclosed |