Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.39 |
| ▸ | ALOX15 | P16050 | 3/20 | 0.39 |
| ▸ | USP2 | O75604 | 2/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | HTR3A | P46098 | 1/20 | 0.38 |
| ▸ | HRH4 | Q9H3N8 | 1/20 | 0.38 |
| ▸ | GBA1 | P04062 | 4/20 | 0.37 |
| ▸ | ESR1 | P03372 | 1/20 | 0.36 |
| ▸ | CTNNB1 | P35222 | 1/20 | 0.36 |
| ▸ | TCF7L2 | Q9NQB0 | 1/20 | 0.36 |
| ▸ | GLA | P06280 | 2/20 | 0.35 |
| ▸ | MAPT | P10636 | 2/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.35 |
| ▸ | HCRTR1 | O43613 | 2/20 | 0.35 |
| ▸ | HCRTR2 | O43614 | 2/20 | 0.35 |
| ▸ | HTT | P42858 | 2/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.34 |
| ▸ | GAA | P10253 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11217766 | 0.89 | HCRTR1 (0.37) | KDM4EALDH1A1HRH4ESR1CTNNB1 | |
| SCHEMBL11197619 | 0.88 | KDM4E (0.35) | KDM4EALDH1A1LMNAHRH4ESR1 | |
| SCHEMBL11203658 | 0.88 | KDM4E (0.37) | KDM4EALDH1A1ALOX15USP2LMNA | |
| SCHEMBL11200451 | 0.88 | LMNA (0.38) | KDM4EALDH1A1LMNAHRH4ESR1 | |
| SCHEMBL11201137 | 0.87 | ESR1 (0.39) | KDM4EALDH1A1ALOX15USP2LMNA | |
| SCHEMBL11207434 | 0.86 | KDM4E (0.38) | KDM4EALDH1A1ESR1CTNNB1TCF7L2 | |
| SCHEMBL11203861 | 0.85 | P2RX3 (0.41) | KDM4EALDH1A1ALOX15USP2LMNA | |
| SCHEMBL11200422 | 0.85 | KDM4E (0.41) | KDM4EALDH1A1ALOX15USP2LMNA | |
| SCHEMBL11198545 | 0.84 | HRH4 (0.42) | KDM4EALDH1A1LMNAHTR3AHRH4 | |
| SCHEMBL11197538 | 0.84 | PRKCI (0.41) | KDM4EALDH1A1ALOX15USP2LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0082023-A2 | Thienopyrimidine derivatives, their preparation and their medical use | SANKYO COMPANY LIMITED (JP) | 1983-06-22 | — | — | EP | disclosed |