SCHEMBL9066299

SCHEMBL9066299

Cc1cc(C2(c3ccc(O)c(C)c3)CCC(c3ccccc3)CC2)ccc1O

nearest known ligand 0.59

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ESR2 Q92731 5/20 0.59
ESR1 P03372 4/20 0.59
MAPT P10636 3/20 0.39
MEN1 O00255 2/20 0.39
LMNA P02545 2/20 0.39
KMT2A Q03164 2/20 0.39
XBP1 P17861 1/20 0.39
NPSR1 Q6W5P4 1/20 0.39
POLB P06746 1/20 0.39
SMN1; SMN2 Q16637 1/20 0.39
TDP1 Q9NUW8 1/20 0.39
L3MBTL1 Q9Y468 1/20 0.39
TRPA1 O75762 1/20 0.38
SIRT1 Q96EB6 1/20 0.36
HSD11B1 P28845 1/20 0.36
ACHE P22303 1/20 0.36
TAS1R3 Q7RTX0 1/20 0.36
TAS1R1 Q7RTX1 1/20 0.36
SLC18A3 Q16572 2/20 0.35
ALDH1A1 P00352 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3807813 0.88 ESR2 (0.59) ESR2ESR1
SCHEMBL30375487 0.88 ESR2 (0.59) ESR2ESR1
SCHEMBL4816643 0.88 ESR2 (0.63) ESR2ESR1MAPTMEN1LMNA
SCHEMBL9075391 0.85 ACHE (0.53) ESR2ESR1MAPTTRPA1SIRT1
SCHEMBL29393324 0.83 ESR1 (0.69) ESR2ESR1MAPTMEN1LMNA
SCHEMBL30165897 0.83 ESR1 (0.69) ESR2ESR1MAPTMEN1LMNA
SCHEMBL4200651 0.83 ESR1 (0.69) ESR2ESR1MAPTMEN1LMNA
SCHEMBL5386114 0.81 ESR1 (0.71) ESR2ESR1MAPTMEN1LMNA
SCHEMBL9065646 0.80 ACHE (0.44) ESR2ESR1MAPTMEN1KMT2A
SCHEMBL673329 0.79 ESR1 (0.85) ESR2ESR1MAPTMEN1LMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0469403-B1 High molecular weight polyester based on 1,1-bis-(4-hydroxyphenyl)-alkylcycloalkanes and thermoplastic blends thereof BAYER AG (DE) 1996-02-28 EP disclosed
EP-0469404-B1 Polyestercarbonates based on 1,1-bis-(4-hydroxyphenyl)-alkylcycloalkanes and thermoplastic blends thereof BAYER AG (DE) 1996-02-28 EP disclosed
EP-0469404-A2 Polyestercarbonates based on 1,1-bis-(4-hydroxyphenyl)-alkylcycloalkanes and thermoplastic blends thereof BAYER AG (DE) 1992-02-05 EP disclosed
US-5034457-A Polycarbonate for use in molding materials for laminated films and for electronics BAYER AKTIENGESELLSCHAFT (DE) 1991-07-23 US disclosed
US-5010163-A Molding materials BAYER AKTIENGESELLSCHAFT (DE) 1991-04-23 US disclosed
EP-0387593-A2 Thermoplastic alloys of polycarbonates based on substituted cyclohexylidenbisphenols BAYER AG (DE) 1990-09-19 EP disclosed
EP-0374630-A2 Polycarbonates from cyclohexylidene diphenols BAYER AG (DE) 1990-06-27 EP disclosed