Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.52 |
| ▸ | LMNA | P02545 | 2/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.51 |
| ▸ | HTT | P42858 | 2/20 | 0.50 |
| ▸ | USP2 | O75604 | 1/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.47 |
| ▸ | HPGD | P15428 | 2/20 | 0.46 |
| ▸ | GLA | P06280 | 1/20 | 0.46 |
| ▸ | GAA | P10253 | 1/20 | 0.46 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.44 |
| ▸ | NTSR1 | P30989 | 1/20 | 0.44 |
| ▸ | TSHR | P16473 | 2/20 | 0.44 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.44 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11200538 | 0.92 | SMN1; SMN2 (0.57) | SMN1; SMN2LMNAALDH1A1HTTUSP2 | |
| SCHEMBL11197946 | 0.89 | NPC1 (0.48) | SMN1; SMN2LMNAALDH1A1HTTKMT2A | |
| SCHEMBL11196667 | 0.85 | USP2 (0.50) | SMN1; SMN2LMNAALDH1A1HTTUSP2 | |
| SCHEMBL11200409 | 0.83 | SMN1; SMN2 (0.49) | SMN1; SMN2LMNAALDH1A1HTTUSP2 | |
| SCHEMBL11196859 | 0.83 | LMNA (0.49) | SMN1; SMN2LMNAALDH1A1HTTUSP2 | |
| SCHEMBL11195599 | 0.82 | KMT2A (0.51) | SMN1; SMN2LMNAALDH1A1KMT2AHPGD | |
| SCHEMBL11200352 | 0.82 | LMNA (0.59) | SMN1; SMN2LMNAALDH1A1KMT2AHPGD | |
| SCHEMBL11198647 | 0.80 | MEN1 (0.55) | SMN1; SMN2LMNAALDH1A1KMT2AHPGD | |
| SCHEMBL11193818 | 0.80 | USP2 (0.47) | SMN1; SMN2LMNAALDH1A1HTTUSP2 | |
| SCHEMBL11200327 | 0.80 | CNR1 (0.50) | SMN1; SMN2LMNAALDH1A1HTTKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4379926-A | DIURETICS | AYERST, MCKENNA & HARRISON LTD. (CA) | 1983-04-12 | — | — | US | disclosed |