Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.59 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.59 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.52 |
| ▸ | POLB | P06746 | 1/20 | 0.47 |
| ▸ | TSHR | P16473 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.47 |
| ▸ | MAPT | P10636 | 2/20 | 0.47 |
| ▸ | MEN1 | O00255 | 1/20 | 0.47 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.47 |
| ▸ | TERT | O14746 | 1/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.46 |
| ▸ | GLA | P06280 | 1/20 | 0.46 |
| ▸ | HPGD | P15428 | 1/20 | 0.46 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11198647 | 0.94 | MEN1 (0.55) | LMNACYP2C19HSD17B10POLBKMT2A | |
| SCHEMBL11200538 | 0.89 | SMN1; SMN2 (0.57) | LMNACYP2C19POLBTSHRKMT2A | |
| SCHEMBL11198673 | 0.89 | ALDH1A1 (0.57) | LMNAPOLBTSHRKMT2AALDH1A1 | |
| SCHEMBL11196192 | 0.82 | POLB (0.49) | LMNAPOLBTSHRKMT2AALDH1A1 | |
| SCHEMBL11200546 | 0.82 | SMN1; SMN2 (0.52) | LMNACYP2C19POLBTSHRKMT2A | |
| SCHEMBL11196667 | 0.82 | USP2 (0.50) | LMNACYP2C19POLBTSHRKMT2A | |
| SCHEMBL11198691 | 0.80 | LMNA (0.50) | LMNACYP2C19ALDH1A1SMN1; SMN2EPHX2 | |
| SCHEMBL11196859 | 0.79 | LMNA (0.49) | LMNAPOLBTSHRALDH1A1NPSR1 | |
| SCHEMBL11200409 | 0.79 | SMN1; SMN2 (0.49) | LMNACYP2C19TSHRKMT2AALDH1A1 | |
| SCHEMBL11200290 | 0.77 | CNR1 (0.44) | LMNAALDH1A1SMN1; SMN2HPGDEPHX2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4379926-A | DIURETICS | AYERST, MCKENNA & HARRISON LTD. (CA) | 1983-04-12 | — | — | US | disclosed |