Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.57 |
| ▸ | LMNA | P02545 | 2/20 | 0.57 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.56 |
| ▸ | HTT | P42858 | 2/20 | 0.55 |
| ▸ | USP2 | O75604 | 1/20 | 0.55 |
| ▸ | GAA | P10253 | 1/20 | 0.50 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.48 |
| ▸ | MEN1 | O00255 | 1/20 | 0.48 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.48 |
| ▸ | TSHR | P16473 | 1/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.48 |
| ▸ | HPGD | P15428 | 1/20 | 0.47 |
| ▸ | MAPT | P10636 | 3/20 | 0.47 |
| ▸ | POLB | P06746 | 2/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11196667 | 0.92 | USP2 (0.50) | SMN1; SMN2LMNAALDH1A1HTTUSP2 | |
| SCHEMBL11200546 | 0.92 | SMN1; SMN2 (0.52) | SMN1; SMN2LMNAALDH1A1HTTUSP2 | |
| SCHEMBL11200409 | 0.90 | SMN1; SMN2 (0.49) | SMN1; SMN2LMNAALDH1A1HTTUSP2 | |
| SCHEMBL11196859 | 0.90 | LMNA (0.49) | SMN1; SMN2LMNAALDH1A1HTTUSP2 | |
| SCHEMBL11200352 | 0.89 | LMNA (0.59) | SMN1; SMN2LMNAALDH1A1CYP2C19MEN1 | |
| SCHEMBL11198647 | 0.87 | MEN1 (0.55) | SMN1; SMN2LMNAALDH1A1GAACYP2C19 | |
| SCHEMBL11193818 | 0.86 | USP2 (0.47) | SMN1; SMN2LMNAALDH1A1HTTUSP2 | |
| SCHEMBL11201975 | 0.86 | USP2 (0.50) | SMN1; SMN2LMNAALDH1A1HTTUSP2 | |
| SCHEMBL11205450 | 0.85 | HTT (0.47) | SMN1; SMN2LMNAALDH1A1HTTUSP2 | |
| SCHEMBL11195599 | 0.85 | KMT2A (0.51) | SMN1; SMN2LMNAALDH1A1GAAMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4379926-A | DIURETICS | AYERST, MCKENNA & HARRISON LTD. (CA) | 1983-04-12 | — | — | US | disclosed |